Genetic Polymorphisms of Xenobiotic Metabolizing Genes (GSTM1 GSTT1 GSTP1) Gene-Gene Interaction with Association to Lung Cancer Risk in North India; A Case Control Study

摘要

In this case control study involving, 220 human subjects; polymorphisms in xenobiotic metabolizing genes ( , and - ) and their association to lung cancer risk is being analysed among smokers and non-smokers. or gene polymorphism and amino acid changes in have been correlated and may be associated to lung cancer risk. Other factor includes exposure to environmental pollutants and life style choices. We have explored gene-gene and gene-environment interaction in the aetiology of lung cancer risk among north Indian population.