Effect of Curcumin on Growth Performance Inflammation Insulin level and Lipid Metabolism in Weaned Piglets with IUGR

摘要

Intrauterine growth retardation (IUGR) has adverse influences on the growth performance and body metabolism of animals. Curcumin, a naturally occurring phenolic compound, has been proven to improve the growth of pigs. However, the studies related to the role of curcumin in treating IUGR piglets are not clear. Therefore, the purpose of our study was to investigate the role of curcumin on the growth, secretion of serum cytokines and hepatic metabolism of IUGR piglets. We found that IUGR piglets are accompanied by impaired growth, inflammation, and insulin resistance, as well as increased hepatic lipid concentrations. Curcumin supplementation improved growth and reduced hepatic inflammatory levels, thereby attenuating insulin resistance and decreasing the hepatic lipid concentration of IUGR piglets.