The aldose reductase inhibitor epalrestat exerts nephritic protection on diabetic nephropathy in db/db mice through metabolic modulation

摘要

Biochemical assay of renal function and histological morphology data in different groups of mice. ( ) Urinary albumin excretions, ( ) creatinine clearance rate, ( ) plasma creatinine levels, ( ) plasma fasting glucose levels, ( ) mesangial matrix fractions, ( ) interstitial fibrosis area ratios, ( ) glomerular basement membranes thickness, ( ) foot process width, ( ) glomerular tuft area. The data are expressed as the mean ± SD. *  P #  db/db group