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Combination of aldose reductase inhibitors and angiotensin-II antagonists for the treatment of diabetic nephropathy
Combination of aldose reductase inhibitors and angiotensin-II antagonists for the treatment of diabetic nephropathy
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机译:醛糖还原酶抑制剂和血管紧张素-II拮抗剂联合治疗糖尿病肾病
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摘要
This invention is directed to methods, pharmaceutical compositions and kits comprising an aldose reductase inhibitor (ARI), a prodrug thereof or a pharmaceutically acceptable salt of said ARI or said prodrug and an antihypertensive agent, a prodrug thereof or a pharmaceutically acceptable salt of said antihypertensive agent or said prodrug. This invention further relates to methods of using those pharmaceutical compositions for the treatment of diabetic complications such as diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, myocardial infarction, cataracts and diabetic cardiomyopathy.
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