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Large-Scale Analysis of Association Between LRP5 and LRP6 Variants and Osteoporosis

机译：LRP5和LRP6变异与骨质疏松症之间关联的大规模分析

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ContextMutations in the low-density lipoprotein receptor-related protein 5 (LRP5) gene cause rare syndromes characterized by altered bone mineral density (BMD). More common LRP5 variants may affect osteoporosis risk in the general population.

机译：低密度脂蛋白受体相关蛋白5（LRP5）基因的突变会导致罕见的综合征，其特征是骨矿物质密度（BMD）改变。更常见的LRP5变异可能会影响普通人群的骨质疏松症风险。

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作者
Joyce B. J. van Meurs; Thomas A. Trikalinos; Stuart H. Ralston; Susana Balcells; Maria Luisa Brandi; Kim Brixen; Douglas P. Kiel; Bente L. Langdahl; Paul Lips; Östen Ljunggren; Roman Lorenc; Barbara Obermayer-Pietsch; Claes Ohlsson; Ulrika Pettersson; David M. Reid; Francois Rousseau; Serena Scollen; Wim Van Hul; Lidia Agueda; Kristina Åkesson; Lidia I. Benevolenskaya; Serge L. Ferrari; Göran Hallmans; Albert Hofman; Lise Bjerre Husted; Marcin Kruk; Stephen Kaptoge; David Karasik; Magnus K. Karlsson; Mattias Lorentzon; Laura Masi; Fiona E. A. McGuigan; Dan Mellström; Leif Mosekilde; Xavier Nogues; Huibert A. P. Pols; Jonathan Reeve; Wilfried Renner; Fernando Rivadeneira; Natasja M. van Schoor; Kurt Weber; John P. A. Ioannidis; André G. Uitterlinden;
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年(卷),期 -1(299),11
年度 -1
页码 1277–1290
总页数 27
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1. Characterization of genetically engineered mouse models carrying Col2a1-cre-induced deletions of Lrp5 and/or Lrp6 [J] . Cassie A Schumacher, Danese M Joiner, Kennen D Less, 骨研究（英文版） . 2015,第004期
2. Characterization of genetically engineered mouse models carrying Col2a1-cre-induced deletions of Lrp5 and/or Lrp6 [J] . Cassie A Schumacher, Danese M Joiner, Kennen D Less, 骨研究：英文 . 2015,第004期
3. Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis. [J] . VAN MEURS Joyce B. J., TRIKALINOS Thomas A., RALSTON Stuart H., JAMA: the Journal of the American Medical Association . 2008,第11期

机译：LRP5和LRP6变异与骨质疏松症之间关联的大规模分析。
4. The involvement of the canonical Wnt-signaling receptor LRP5 and LRP6 gene variants with ADHD and sexual dimorphism: Association study and meta-analysis [J] . Gruenblatt Edna, Nemoda Zsofia, Werling Anna Maria, American journal of medical genetics, Part B. Neuropsychiatric genetics: the official publication of the International Society of Psychiatric Genetics . 2019,第6期

机译：典型WNT-信号传导受体LRP5和LRP6基因变异与ADHD和性二剖形的参与：关联研究和荟萃分析
5. Wnt receptors, bone mass, and fractures: gene-wide association analysis of LRP5 and LRP6 polymorphisms with replication [J] . José A Riancho, José M Olmos, Bego?a Pineda, European journal of endocrinology . 2011,第1期

机译：Wnt受体，骨量和骨折：LRP5和LRP6多态性与复制的全基因关联分析
6. Medical Big Data Analysis System to Discover Associations between Genetic Variants and Diseases [C] . Daehee Kim, Stephanie Gamboa, Vanessa Hernandez, IEEE International Conference on Communications . 2021

机译：医疗大数据分析系统发现遗传变异与疾病之间的关联
7. LARVA - An Integrative Framework for Large-scale Analysis of Recurrent Variants in Noncoding Annotations - And Other Tools for Cancer Genome Analysis. [D] . Lochovsky, Lucas Sze-wan Fong. 2015

机译：LARVA-大规模分析非编码注释中重复变量的综合框架-以及其他用于癌症基因组分析的工具。
8. The involvement of the canonical Wnt‐signaling receptor LRP5 and LRP6 gene variants with ADHD and sexual dimorphism: Association study and meta‐analysis [O] . Edna Grünblatt, Zsofia Nemoda, Anna Maria Werling, -1

机译：典型的Wnt信号受体LRP5和LRP6基因变异与ADHD和性二态性的关系：关联研究和荟萃分析
9. Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis. [O] . van Meurs, JB, Trikalinos, TA, Ralston, SH, 2008

机译：LRP5和LRP6变异与骨质疏松症之间关联的大规模分析。

Large-Scale Analysis of Association Between LRP5 and LRP6 Variants and Osteoporosis

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