Chemoprevention of Lung Carcinogenesis in Addicted Smokers and Ex-Smokers

摘要

Chemoprevention of lung carcinogenesis is one approach to controlling the epidemic of lung cancer caused by cigarette smoking. The target for chemoprevention should be the activities of the multiple carcinogens, toxicants, co-carcinogens, tumor promoters and inflammatory compounds in cigarette smoke. There are presently many agents both synthetic and naturally occurring that prevent lung tumor development in well established animal models. It seems likely that logically constructed mixtures of these agents, developed from the ground up, will be necessary for prevention of lung carcinogenesis