IMPROVING THE RELIABILITY OF STROKE DISABILITY GRADING IN CLINICAL TRIALS AND CLINICAL PRACTICE: THE RANKIN FOCUSED ASSESSMENT (RFA)

摘要

BackgroundThe modified Rankin scale (mRS) rates global disability after stroke and is the most comprehensive and widely employed primary outcome measure in acute stroke trials. However, substantial inter observer variability in mRS scoring has been reported. This study sought to develop and validate a short, practicable structured assessment that would enhance inter-rater reliability.