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Bariatric Surgery and Type 2 Diabetes Mellitus: Surgically Induced Remission

机译:减肥手术和2型糖尿病:手术诱发的缓解

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摘要

The relationship between obesity and type 2 diabetes mellitus (T2DM) is well known. Morbidly obese patients with T2DM who undergo bariatric surgery have improvement or remission of their diabetes. Different types of bariatric operations offer varying degrees of T2DM remission. These operations are classified as restrictive, malabsorptive, or a combination of both. The gold-standard operation, known as the Roux-en-Y gastric bypass, is a combination operation.Most often, improvement of the diabetes is seen within days of the operation. Various theories to explain this rapid change include calorie restriction and hormonal changes from exclusion of the upper gastrointestinal tract. Weight loss accounts for the sustained improvements in glucose control. The patients who benefit the most are those who are early in their disease course.Having a single treatment for both obesity and T2DM is ideal. As bariatric surgery has become a safe operation when performed by experienced surgeons, it should be considered a treatment for these diseases. The impact it can have on the lives of individual patients and society as a whole is tremendous.
机译:肥胖与2型糖尿病(T2DM)之间的关系是众所周知的。进行减肥手术的病态肥胖的T2DM患者可改善或缓解糖尿病。不同类型的减肥手术可提供不同程度的T2DM缓解。这些操作被分为限制性的,吸收不良的或两者的组合。黄金标准的手术称为Roux-en-Y胃旁路手术,是一项联合手术,多数情况下,在手术后几天内即可看到糖尿病的改善。解释这种快速变化的各种理论包括卡路里限制和排除上消化道引起的激素变化。体重减轻是葡萄糖控制持续改善的原因。受益最大的患者是那些病情较早的患者。对肥胖症和T2DM进行单一治疗是理想的选择。由于减肥手术已由经验丰富的外科医师进行,已成为一项安全的手术,因此应考虑对这些疾病进行治疗。它可能对单个患者的生命以及整个社会产生巨大影响。

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