Surgery: Remission of type 2 diabetes mellitus after bariatric surgery - Is it durable?

摘要

Two teams of researchers have evaluated the long-term effects of bariatric surgery on remission of type 2 diabetes mellitus (T2DM) in adults with severe obesity (BMI >=35kg/m~). In the first study, Jimenez et al. assessed the durability of T2DM remission after bariatric surgery and the predictors of T2DM remission and recurrence after surgery. The researchers followed up 153 individuals with T2DM and severe obesity for 35.4 +- 13.5 months after they underwent sleeve gastrectomy or Roux-en-Y gastric bypass surgery. The rate of remission of T2DM was 66% for participants at their last follow-up visit, and was comparable for the two surgical techniques. Predictors of a lack of remission of T2DM after surgery included a long duration of T2DM, high HbA_(1c) level, insulin treatment at study entry and low excess weight loss at last follow-up. Predictors of recurrence of T2DM after surgery included insulin use and weight regain after remission.