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G Protein-coupled Receptor Kinase-5 Attenuates Atherosclerosis by Regulating Receptor Tyrosine Kinases and 7-transmembrane Receptors

机译：G蛋白偶联受体激酶-5通过调节受体酪氨酸激酶和7种跨膜受体来衰减动脉粥样硬化

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ObjectiveG protein-coupled receptor kinase-5 (GRK5) is a widely expressed Ser/Thr kinase that regulates several atherogenic receptors, and may activate or inhibit NFκB. This study sought to determine whether and by what mechanisms GRK5 affects atherosclerosis.

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期刊名称 other
作者
Jiao-Hui Wu; Lisheng Zhang; Alexander C. Fanaroff; Xinjiang Cai; Krishn C. Sharma; Leigh Brian; Sabrina T. Exum; Sudha K. Shenoy; Karsten Peppel; Neil J. Freedman;
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年(卷),期 -1(32),2
年度 -1
页码 308–316
总页数 20
原文格式 PDF
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关键词
signal transduction receptor tyrosine kinases smooth muscle cells endothelial cells macrophages;

机译：信号转导;受体酪氨酸激酶;平滑肌细胞;内皮细胞;巨噬细胞;

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专利

1. G protein-coupled receptor kinase-5 attenuates atherosclerosis by regulating receptor tyrosine kinases and 7-transmembrane receptors. [J] . Wu JH, Zhang L, Fanaroff AC, Arteriosclerosis, thrombosis, and vascular biology . 2012 ,第2期

机译：G蛋白偶联受体激酶5通过调节受体酪氨酸激酶和7个跨膜受体来减轻动脉粥样硬化。
2. Interactions between Type III receptor tyrosine phosphatases and growth factor receptor tyrosine kinases regulate tracheal tube formation in Drosophila Interactions between Type III receptor tyrosine phosphatases and growth factor receptor tyrosine kinases regulate tracheal tube formation in Drosophila Interactions between Type III receptor tyrosine phosphatases and growth factor receptor tyrosine kinases regulate tracheal tube formation in Drosophila [J] . Mili Jeon, Kai Zinn, Matthew P. Scott Biology Open . 2012 ,第6期

机译：III型受体酪氨酸磷酸酶和生长因子受体酪氨酸激酶之间的相互作用调节果蝇中的气管管形成相互作用III型受体酪氨酸磷酸酶和生长因子受体酪氨酸激酶之间的相互作用调节果蝇中的气管导管形成III型受体酪氨酸磷酸酶和生长因子受体酪氨酸之间的相互作用激酶调节果蝇气管导管形成
3. Connective tissue growth factor/CCN2 attenuates β-adrenergic receptor responsiveness and cardiotoxicity by induction of G protein-coupled receptor kinase-5 in cardiomyocytes [J] . Molecular pharmacology. . 2013 ,第3期

机译：结缔组织生长因子/ CCN2通过诱导心肌细胞中G蛋白偶联受体激酶5减弱β-肾上腺素受体反应性和心脏毒性
4. G PROTEIN-COUPLED RECEPTOR KINASE TYPE 4 (GRK4) GENE VARIANTS AND RESPONSE TO ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKER THERAPY [C] . Hironobu Sanada, Junichi Yatabe, Midori Sasaki Yatabe, 9th International Symposium on Salt(第九届世界盐业大会）论文集 . 2009

机译：G蛋白偶联的4型受体激酶（GRK4）基因变异和对血管紧张素II 1型受体阻滞剂的反应
5. G Protein-Coupled Receptor Kinase 2 (GRK2) and Toll-like Receptors as Regulators of Central Sensitization in Fibromyalgia and Chronic Temporomandibular Disorders [D] . Angkanawaraphan, Lalilta. 2018

机译：G蛋白偶联受体激酶2（GRK2）和Toll样受体作为纤维肌痛和慢性颞下颌关节疾病中枢敏化的调节剂。
6. G protein-coupled receptor kinase-5 regulates thrombin-activated signaling in endothelial cells [O] . Chinnaswamy Tiruppathi, Weihong Yan, Raudel Sandoval, 2000

机译：G蛋白偶联受体激酶5调节内皮细胞中的凝血酶激活信号
7. G Protein–Coupled Receptor Kinase-5 Attenuates Atherosclerosis by Regulating Receptor Tyrosine Kinases and 7-Transmembrane Receptors [O] . Jiao-Hui Wu, Lisheng Zhang, Alexander C. Fanaroff, 2012

机译：G蛋白偶联受体激酶-5通过调节受体酪氨酸激酶和7种跨膜受体来衰减动脉粥样硬化

G Protein-coupled Receptor Kinase-5 Attenuates Atherosclerosis by Regulating Receptor Tyrosine Kinases and 7-transmembrane Receptors

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