Transcriptomic Assay of CD8+ T Cells in Treatment-Naïve HIV HCV-Mono-Infected and HIV/HCV-Co-Infected Chinese

摘要

BackgroundCo-infection with HIV and HCV is very common. It is estimated that over 5 million people are co-infected with HIV and HCV worldwide. Accumulated evidence shows that each virus alters the course of infection of the other one. CD8+ T cells play a crucial role in the eradication of viruses and infected target cells. To the best of our knowledge, no one has investigated the gene expression profiles in HIV/HCV-co-infected individuals.