Silencing of IQGAP1 by shRNA inhibits the invasion of ovarian carcinoma HO-8910PM cells in vitro

机译：shRNA沉默IQGAP1可抑制卵巢癌细胞HO-8910PM的侵袭

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BackgroundIQGAP1 is a scaffolding protein and overexpressed in many human tumors, including ovarian cancer. However, the contribution of IQGAP1 to invasive properties of ovarian cancer cells remains unknown. Here, we investigated the effect of IQGAP1-specific short hairpin RNA (shRNA) expressing plasmids on metastatic potential of ovarian cancer HO-8910PM cells.

机译：背景IQGAP1是一种支架蛋白，在许多人类肿瘤（包括卵巢癌）中过表达。但是，IQGAP1对卵巢癌细胞侵袭特性的贡献仍然未知。在这里，我们调查了IQGAP1特异性短发夹RNA（shRNA）表达质粒对卵巢癌HO-8910PM细胞转移潜能的影响。

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期刊名称 Journal of Experimental Clinical Cancer Research : CR
作者
Pei-Xin Dong; Nan Jia; Zhu-Jie Xu; Ying-Tao Liu; Da-Jin Li; You-Ji Feng;
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作者单位

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年(卷),期 2008(27),1
年度 2008
页码 77
总页数 8
原文格式 PDF
正文语种
中图分类肿瘤学;
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专利

1. Silencing of IQGAP1 by shRNA inhibits the invasion of ovarian carcinoma HO-8910PM cells in vitro [J] . Pei-Xin Dong, Nan Jia, Zhu-Jie Xu, Journal of experimental & clinical cancer research : . 2008,第1期

机译：shRNA沉默IQGAP1可抑制卵巢癌细胞HO-8910PM的侵袭
2. Knockdown of Long Noncoding RNA NR_026689 Inhibits Proliferation and Invasion and Increases Apoptosis in Ovarian Carcinoma HO-8910PM Cells [J] . Zhang Xin, Li Shaowen, Dong Chunli, Oncology Research . 2017,第2期

机译：长度非编码RNA NR_026689的敲低抑制增殖和侵袭，并增加卵巢癌HO-8910PM细胞中的细胞凋亡
3. IQGAP1 gene silencing induces apoptosis and decreases the invasive capacity of human hepatocellular carcinoma cells [J] . Zoheir Khairy M. A., Abd-Rabou Ahmed A., Harisa Gamaleldin I., Tumour biology : . 2016,第10期

机译：IQGAP1基因沉默诱导细胞凋亡并降低人肝癌细胞的侵袭能力
4. Inhibitory Effects of Natural Food Dyes Genistein on Invasion of SK0V3 Human Ovarian Carcinoma Cells in vivo and in vitro [C] . Tang Li, Li Yu International Conference on Chemical Engineering and Advanced Materials . 2013

机译：天然食品染料Genistein在体内和体外侵袭SK0v3人卵癌细胞侵袭的抑制作用
5. Human Hepatocellular Carcinoma Cells Adapt to ASCT2 and LAT1 Amino Acid Transporter Knockdown Mediated by ShRNA and CRISPR-Cas9 [D] . Bothwell, Paige Jay 2017

机译：人肝癌细胞适应ShRNA和CRISPR-Cas9介导的ASCT2和LAT1氨基酸转运蛋白敲低
6. Reactivation of epigenetically silenced miR-124 reverses the epithelial-to-mesenchymal transition and inhibits invasion in endometrial cancer cells via the direct repression of IQGAP1 expression [O] . Peixin Dong, Kei Ihira, Ying Xiong, 2016

机译：表观遗传沉默的miR-124的重新激活通过直接抑制IQGAP1表达来逆转上皮向间充质转化并抑制子宫内膜癌细胞的侵袭
7. Silencing of IQGAP1 by shRNA inhibits the invasion of ovarian carcinoma HO-8910PM cells in vitro [O] . 2008

机译：shRNA沉默IQGAP1可抑制卵巢癌细胞HO-8910PM的侵袭

Silencing of IQGAP1 by shRNA inhibits the invasion of ovarian carcinoma HO-8910PM cells in vitro

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