Chronic Temporomandibular Disorder Is Not Necessarily Associated with a Compromised Endogenous Analgesic System

摘要

AimsOur previous work demonstrated that women with temporomandibular disorder (TMD) exhibit enhanced temporal summation of pain upon repetitive mechanical stimulation of the fingers, compared to healthy controls, suggestive of widespread up regulated central nociceptive processing in this patient population. The current study asks whether TMD case-control differences in Conditioned Pain Modulation (CPM) exist, using a mechanically evoked Temporal Summation (TS) model.