Essential Tremor 10 20 30 40: Clinical Snapshots of the Disease by Decade of Duration

摘要

BackgroundEssential tremor (ET) is a chronic, progressive neurological disorder in which disease burden may slowly accrue. There are few long-term studies, and the clinical and functional status of patients, with each decade of disease duration, has not been documented in detail. We used cross-sectional data on 335 ET patients (disease duration 1–81 years) to produce clinical snapshots of the disease at each 10-year milestone (i.e., <10, 10, 20, 30 and ≥40 years). We hope these data will be of value in clinical-prognostic settings both to patients and their treating physicians.