Fever After Rewarming: Incidence of Pyrexia in Post-Cardiac Arrest Patients who have Undergone Mild Therapeutic Hypothermia

摘要

BackgroundInduction of mild therapeutic hypothermia, or TH (temperature 32–34°C), has become standard of care in many hospitals for comatose survivors of cardiac arrest. Pyrexia, or fever, is known to be detrimental in patients with neurologic injuries such as stroke or trauma. The incidence of pyrexia in the post-rewarming phase of TH is unknown. We attempted to determine the incidence of fever after TH, and hypothesized that those patients who were febrile after rewarming would have worse clinical outcomes than those who maintained normothermia in the post-rewarming period.