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Preclinical Comparison of Near-Infrared-Labeled Cetuximab and Panitumumab for Optical Imaging of Head and Neck Squamous Cell Carcinoma

机译：近红外标记西妥昔单抗和帕尼单抗用于头颈部鳞状细胞癌光学成像的临床前比较

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摘要

Purpose:Though various targets have been proposed and evaluated, no agent has yet been investigated in a clinical setting for head and neck cancer. The present study aimed to compare two fluorescently labeled anti-epidermal growth factor receptor (EGFR) antibodies for detection of head and neck squamous cell carcinoma (HNSCC).

机译：目的：尽管已经提出并评估了各种靶标，但尚未在临床上研究任何药物治疗头颈癌。本研究旨在比较两种荧光标记的抗表皮生长因子受体（EGFR）抗体，用于检测头颈部鳞状细胞癌（HNSCC）。

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期刊名称 other
作者
Kristine E. Day; Larissa Sweeny; Brian Kulbersh; Kurt R. Zinn; Eben L. Rosenthal;
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年(卷),期 -1(15),6
年度 -1
页码 722–729
总页数 16
原文格式 PDF
正文语种
中图分类
关键词
Aerodigestive squamous cell carcinoma Head and neck Near-infrared imaging Epidermal growth factor receptor;

机译：消化道鳞状细胞癌;头颈;近红外成像;表皮生长因子受体;

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专利

1. Preclinical comparison of near-infrared-labeled cetuximab and panitumumab for optical imaging of head and neck squamous cell carcinoma [J] . DayK.E., SweenyL., KulbershB., Molecular imaging and biology: MIB : the official publication of the Academy of Molecular Imaging . 2013,第6期

机译：近红外标记西妥昔单抗和帕尼单抗对头颈部鳞状细胞癌的光学成像的临床前比较
2. The hypoxic tumor microenvironment and drug resistance against EGFR inhibitors: preclinical study in cetuximab-sensitive head and neck squamous cell carcinoma cell lines [J] . Carolien Boeckx, Jolien Van den Bossche, Ines De Pauw, BMC research notes . 2015,第1期

机译：低氧肿瘤微环境和对EGFR抑制剂的耐药性：西妥昔单抗敏感的头颈部鳞状细胞癌细胞系的临床前研究
3. The hypoxic tumor microenvironment and drug resistance against EGFR inhibitors: preclinical study in cetuximab-sensitive head and neck squamous cell carcinoma cell lines [J] . Carolien Boeckx, Jolien Van den Bossche, Ines De Pauw, BMC research notes . 2015,第1期

机译：低氧肿瘤微环境和对EGFR抑制剂的耐药性：西妥昔单抗敏感的头颈部鳞状细胞癌细胞系的临床前研究
4. Interstitial photodynamic therapy in combination with Cetuximab for recurrent head and neck squamous cell carcinoma [C] . Nestor Rigual, Ambujakshan Dildeep, Gal Shafirstein Conference on photonic therapeutics and diagnostics IX . 2013

机译：间质性光动力疗法联合西妥昔单抗治疗复发性头颈部鳞状细胞癌
5. Non-invasive in vivo assessment of tumor hypoxia using functional magnetic resonance (fMR) imaging during therapy in human head and neck squamous cell carcinoma (HNSCC) xenografts: Implications for assessing therapeutic efficacy. [D] . Bhattacharya, Arup. 2005

机译：在人头颈部鳞状细胞癌（HNSCC）异种移植物治疗期间，使用功能性磁共振（fMR）成像对肿瘤缺氧进行非侵入性体内评估：评估治疗功效的意义。
6. The hypoxic tumor microenvironment and drug resistance against EGFR inhibitors: preclinical study in cetuximab-sensitive head and neck squamous cell carcinoma cell lines [O] . Carolien Boeckx, Jolien Van den Bossche, Ines De Pauw, 2015

机译：低氧肿瘤微环境和对EGFR抑制剂的耐药性：西妥昔单抗敏感的头颈部鳞状细胞癌细胞系的临床前研究
7. Preclinical Comparison of Near-Infrared-Labeled Cetuximab and Panitumumab for Optical Imaging of Head and Neck Squamous Cell Carcinoma [O] . Kristine E. Day, Larissa Sweeny, Brian Kulbersh, 2013

机译：近红外标记的近红外标记的颈鳞和颈部鳞状细胞癌光学成像的临床前比较

Preclinical Comparison of Near-Infrared-Labeled Cetuximab and Panitumumab for Optical Imaging of Head and Neck Squamous Cell Carcinoma

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