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Alcohol and Drug Use Outcomes Among Vulnerable Women Living with HIV: Results from the Western Cape Women’s Health CoOp

机译:易感染艾滋病毒的女性中的酒精和药物使用结果:西开普省妇女健康合作社的结果

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摘要

Alcohol and other drug use can negatively affect adherence to and retention in antiretroviral therapy (ART) among people living with HIV. Yet, there are few brief interventions that reduce these behaviors among this population. This article presents the findings from a randomized field experiment that assessed the effects of a woman-focused intervention (the Women’s Health CoOp [WHC]) on reducing alcohol and other drug use among vulnerable women in Cape Town, South Africa. The analyses were limited to 84 women living with HIV who reported drinking alcohol at baseline. Because of the small sample size, analyses were performed using an exact logistic regression procedure. At 12-month follow-up, women in the WHC arm were more likely to be abstinent from alcohol (Odds Ratio [OR] = 3.61; 95% Confidence Intervals [CI] = 1.23, 11.70; p = 0.016) and somewhat more likely to test negative for other drugs (OR = 3.07; 95% CI = 0.83,12.31; p = 0.105), compared with women in the comparison arms. This study provides preliminary evidence of the efficacy of a brief, woman-focused intervention in reducing alcohol and other drug use among vulnerable women living with HIV and it has implications for HIV treatment.
机译:酒精和其他药物的使用会对艾滋病毒感染者对抗逆转录病毒疗法(ART)的依从性和保留率产生负面影响。但是,很少有简短的干预措施可以减少这些人群中的这些行为。本文介绍了一项随机野外实验的结果,该实验评估了南非开普敦以妇女为中心的干预措施(Women's Health CoOp [WHC])对减少酗酒和其他毒品使用的影响。该分析仅限于84名报告基线饮酒的HIV感染妇女。由于样本量较小,因此使用精确的逻辑回归程序进行分析。在12个月的随访中,WHC组中的女性戒酒的可能性更高(赔率[OR] = 3.61; 95%的置信区间[CI] = 1.23,11.70; p = 0.016),并且更有可能戒酒与其他比较组中的女性相比,其他药物测试阴性(OR = 3.07; 95%CI = 0.83,12.31; p = 0.105)。这项研究提供了一个简短的,以妇女为中心的干预措施,以减少感染艾滋病毒的脆弱妇女的酗酒和其他毒品使用的有效性,并为艾滋病治疗带来了影响。

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