Minimizing lipid signal bleed in brain 1H chemical shift imaging by post-acquisition grid shifting

摘要

PurposeLow spatial resolution in conventional ¹H brain chemical shifting imaging (CSI) studies causes partial volume error (PVE) or signal ‘bleed’ that is especially deleterious to voxels near the scalp. The standard spatial apodization approach adversely affects spatial resolution. Here, a novel automated post-processing strategy of partial volume correction employing grid shifting (‘PANGS’) is presented, which minimizes residual PVE without compromising spatial resolution.