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Overexpression of ERG and Wild-Type PTEN Are Associated with Favorable Clinical Prognosis and Low Biochemical Recurrence in Prostate Cancer

机译：ERG和野生型PTEN的过表达与前列腺癌的临床预后良好和生化复发率低相关

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ObjectivesThe aim of this study was to investigate the expression of two commonly altered genes ERG and PTEN in prostate cancer (PC) and evaluate their prognostic significance. Despite conflicting published results, TMPRSS2-ERG gene fusion and PTEN loss are generally considered unfavorable markers for PC progression.

机译：目的本研究的目的是研究两种经常改变的基因ERG和PTEN在前列腺癌（PC）中的表达并评估其预后意义。尽管发表了相互矛盾的结果，但TMPRSS2-ERG基因融合和PTEN丢失通常被认为是PC病情发展的不利标志。

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期刊名称 other
作者
Sung Han Kim; Soo Hee Kim; Jae Young Joung; Geon Kook Lee; Eun Kyung Hong; Kyung Min Kang; Ami Yu; Byung Ho Nam; Jinsoo Chung; Ho Kyung Seo; Weon Seo Park; Kang Hyun Lee;
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年(卷),期 -1(10),4
年度 -1
页码 e0122498
总页数 13
原文格式 PDF
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专利

1. Cysteine-rich secretory protein 3 overexpression is linked to a subset of PTEN-deleted ERG fusion-positive prostate cancers with early biochemical recurrence [J] . Katharina Grupp, Sebastian Kohl, Hüseyin Sirma, Modern Pathology . 2013,第5期

机译：富含半胱氨酸的分泌蛋白3过表达与PTEN缺失的ERG融合阳性前列腺癌的一部分具有早期生化复发相关
2. Association of ERG/PTEN status with biochemical recurrence after radical prostatectomy for clinically localized prostate cancer [J] . Mehra Rohit, Salami Simpa S., Lonigro Robert, Medical oncology . 2018,第12期

机译：临床局部前列腺癌自由基前列腺切除术后ERG / PTEN状态与生物化学复发的关联
3. Prognostic value of ERG, PTEN, CRISP3 and SPINK1 in predicting biochemical recurrence in prostate cancer [J] . Noh Byeong-Joo, Sung Ji-Youn, Kim Youn Wha, Oncology letters . 2016,第6aPta1期

机译：ERG，PTEN，CRISP3和SPINK1在预测前列腺癌生化复发中的预后价值
4. Computer extracted texture features on T2w MRI to predict biochemical recurrence following radiation therapy for prostate cancer [C] . Shoshana B. Ginsburg, Mirabela Rusu, John Kurhanewicz, Conference on computer-aided diagnosis . 2014

机译：T2w MRI上计算机提取的纹理特征可预测前列腺癌放射治疗后的生化复发
5. Effect of Genetic Background on the Initiation and Progression of Mouse Prostate Cancer Driven by MYC Overexpression and PTEN Loss [D] . Chin, Alexander. 2021

机译：遗传背景对MYC过表达和PTEN损失驱动的小鼠前列腺癌的启动与进展
6. Favorable Biochemical Freedom From Recurrence With Stereotactic Body Radiation Therapy for Intermediate and High-Risk Prostate Cancer: A Single Institutional Experience With Long-Term Follow-Up [O] . Anthony Ricco, Gabrielle Barbera, Rachelle Lanciano, 2020

机译：良好的生物化学自由与常规体内放射疗法的中间体和高风险前列腺癌的疗程：单一的制度经验长期随访
7. Overexpression of ERG and Wild-Type PTEN Are Associated with Favorable Clinical Prognosis and Low Biochemical Recurrence in Prostate Cancer. [O] . Sung Han Kim, Soo Hee Kim, Jae Young Joung, 2015

机译：ERG和野生型pTEN的过度表达与前列腺癌的有利临床预后和低生化复发相关。

Overexpression of ERG and Wild-Type PTEN Are Associated with Favorable Clinical Prognosis and Low Biochemical Recurrence in Prostate Cancer

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