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Large Sparse Optimal Matching with Refined Covariate Balance in anObservational Study of the Health Outcomes Produced by New Surgeons

机译:大型稀疏最优匹配与细协变量平衡新医生产生的健康结果的观察性研究

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摘要

Every newly trained surgeon performs her first unsupervised operation. How do the health outcomes of her patients compare with the patients of experienced surgeons? Using data from 498 hospitals, we compare 1252 pairs comprised of a new surgeon and an experienced surgeon working at the same hospital. We introduce a new form of matching that matches patients of each new surgeon to patients of an otherwise similar experienced surgeon at the same hospital, perfectly balancing 176 surgical procedures and closely balancing a total of 2.9 million categories of patients; additionally, the individual patient pairs are as close as possible. A new goal for matching is introduced, called “refined covariate balance,” in which a sequence of nested, ever more refined, nominal covariates is balanced as closely as possible, emphasizing the first or coarsest covariate in that sequence. A new algorithm for matching is proposed and the main new results prove that the algorithm finds the closest match in terms of the total within-pair covariate distances among all matches that achieve refined covariate balance. Unlike previous approaches to forcing balance on covariates, the new algorithm creates multiple paths to a match in a network, where paths that introduce imbalances are penalized and hence avoided to the extent possible. The algorithm exploits a sparse network to quickly optimize a match that is about two orders of magnitude larger than istypical in statistical matching problems, thereby permitting much more extensive use offine and near-fine balance constraints. The match was constructed in a few minutes using anetwork optimization algorithm implemented in R. An R package called rcbalanceimplementing the method is available from CRAN.
机译:每个新受训的外科医生都将执行她的第一个无人看管的手术。与经验丰富的外科医生相比,她的患者的健康状况如何?使用来自498家医院的数据,我们比较了1252对患者,其中包括新医生和在同一家医院工作的经验丰富的医生。我们引入了一种新的匹配形式,可将每个新医生的患者与同一家医院中其他经验类似的医生的患者进行匹配,从而完美地平衡了176个手术程序,并紧密平衡了290万患者类别;另外,各个患者对尽可能地靠近。引入了一个新的匹配目标,称为“精炼协变量平衡”,在该目标中,尽可能紧密地平衡嵌套的,更精炼的名义协变量序列,强调该序列中的第一个或最粗糙的协变量。提出了一种新的匹配算法,主要的新结果证明,该算法根据所有达到精炼协变量平衡的匹配之间的总对内协变量距离找到最接近的匹配。与以前在协变量上强制平衡的方法不同,新算法在网络中创建了多个匹配路径,因此引入不平衡的路径会受到惩罚,因此要尽可能避免。该算法利用稀疏网络来快速优化匹配,匹配度比匹配度大约两个数量级。统计匹配问题中的典型值,从而允许更广泛地使用精细和接近精细的平衡约束。这场比赛是在几分钟内使用R中实现的网络优化算法。一个名为rcbalance的R包可从CRAN获得实现该方法的方法。

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