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INHALED ALPHA1-PROTEINASE INHIBITOR THERAPY IN PATIENTS WITH CYSTIC FIBROSIS

机译：囊性纤维化患者吸入α1-蛋白酶抑制剂的治疗

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摘要

BackgroundInhaled alpha1-proteinase inhibitor (PI) is known to reduce neutrophil elastase burden in some patients with CF. This phase 2a study was designed to test inhaled Alpha-1 HC, a new aerosolized alpha1-PI formulation, in CF patients.

机译：背景已知吸入α1-蛋白酶抑制剂（PI）可以减轻某些CF患者的嗜中性白细胞弹性蛋白酶负担。这项2a期研究旨在测试CF患者的吸入Alpha-1 HC（一种新型雾化的alpha1-PI制剂）。

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期刊名称 other
作者
Amit Gaggar; Junliang Chen; James F Chmiel; Henry L Dorkin; Patrick A Flume; Rhonda Griffin; David Nichols; Scott H Donaldson;
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年(卷),期 -1(15),2
年度 -1
页码 227–233
总页数 14
原文格式 PDF
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专利

1. Lung deposition of inhaled alpha1-proteinase inhibitor in cystic fibrosis and alpha1-antitrypsin deficiency. [J] . Brand P, Schulte M, Wencker M The European respiratory journal : . 2009,第2期

机译：吸入性α1-蛋白酶抑制剂的肺沉积在囊性纤维化和α1-抗胰蛋白酶缺乏症中。
2. Lung deposition of inhaled Alpha-1-proteinase inhibitor (Alpha₁-PI) - problems and experience of Alpha₁-PI inhalation therapy in patients with hereditary Alpha₁-PI deficiency and cystic fibrosis [J] . R Siekmeier European journal of medical research. . 2010,第Suppla2期

机译：吸入的Alpha-1-蛋白酶抑制剂（Alpha _{1 -PI）的肺沉积-遗传性Alpha _{1患者吸入Alpha _{1 -PI的问题和体会 -PI缺乏症和囊性纤维化}}}
3. Inhaled alpha(1)-proteinase inhibitor therapy in patients with cystic fibrosis [J] . Gaggar Amit, Chen Junliang, Chmiel James F., Journal of cystic fibrosis: official journal of the European Cystic Fibrosis Society . 2016,第2期

机译：吸入性α（1）-蛋白酶抑制剂治疗囊性纤维化患者
4. OMICS approaches to reveal Burkholderia cenocepacia adaptive strategies to long-term residence in the lungs of cystic fibrosis patients under antibiotic therapy [C] . Madeira Andreia, Mira Nuno P, Santos Pedro M, 1st Portuguese Meeting in Bioengineering . 2011

机译：OMICS方法揭示在抗生素治疗下囊性纤维化患者长期驻留在肺泡中的伯克霍尔德菌种的适应策略
5. Cystic Fibrosis Transmembrane Conductance Regulator Modulator Therapies in Cystic Fibrosis: A Retrospective Evaluation of a Nationwide Specialty Pharmacy Database [D] . Mehta, Zumi . 2020

机译：囊性纤维化跨膜电导调节剂调节剂患者囊性纤维化：全国特色药房数据库的回顾性评估
6. Lung deposition of inhaled Alpha-1-proteinase inhibitor (Alpha1-PI) - problems and experience of Alpha1-PI inhalation therapy in patients with hereditary Alpha1-PI deficiency and cystic fibrosis [O] . R Siekmeier 2010

机译：吸入的Alpha-1-蛋白酶抑制剂（Alpha1-PI）的肺沉积-遗传性Alpha1-PI缺乏症和囊性纤维化患者的Alpha1-PI吸入疗法存在的问题和经验
7. Lung deposition of inhaled Alpha-1-proteinase inhibitor (Alpha1-PI) - problems and experience of Alpha1-PI inhalation therapy in patients with hereditary Alpha1-PI deficiency and cystic fibrosis [O] . R. Siekmeier 2010

机译：吸入α-1蛋白酶抑制剂（α1-PI）的肺部沉积 - 遗传α1-PI缺乏症患者α1-PI吸入治疗的问题及体验及囊性纤维化

INHALED ALPHA1-PROTEINASE INHIBITOR THERAPY IN PATIENTS WITH CYSTIC FIBROSIS

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