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Using Blocked Fractional Factorial Designs to Construct Discrete Choice Experiments for Health Care Studies

机译:使用封闭式分数阶因子设计构建用于卫生保健研究的离散选择实验

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摘要

Discrete choice experiments (DCEs) are increasingly used for studying and quantifying subjects preferences in a wide variety of health care applications. They provide a rich source of data to assess real-life decision making processes, which involve trade-offs between desirable characteristics pertaining to health and health care, and identification of key attributes affecting health care.The choice of the design for a DCE is critical because it determines which attributes’ effects and their interactions are identifiable. We apply blocked fractional factorial designs to construct DCEs and address some identification issues by utilizing the known structure of blocked fractional factorial designs. Our design techniques can be applied to several situations including DCEs where attributes have different number of levels. We demonstrate our design methodology using two health care studies to evaluate (1) asthma patients’ preferences for symptom-based outcome measures, and (2) patient preference for breast screening services.
机译:离散选择实验(DCE)越来越多地用于研究和量化各种医疗保健应用中的受试者偏好。它们为评估现实生活中的决策过程提供了丰富的数据源,其中涉及在与健康和医疗保健相关的理想特征之间进行权衡,以及确定影响医疗保健的关键属性.DCE的设计选择至关重要因为它确定了哪些属性的影响及其相互作用是可识别的。我们应用封闭式分数阶析出设计来构建DCE,并利用封闭式分数阶析出设计的已知结构来解决一些识别问题。我们的设计技术可应用于多种情况,包括属性具有不同数量级别的DCE。我们通过两项医疗保健研究来证明我们的设计方法,以评估(1)哮喘患者对基于症状的结局指标的偏爱,以及(2)患者对乳腺筛查服务的偏爱。

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