Higher Expression of CCL2 CCL4 CCL5 CCL21 and CXCL8 Chemokines in the Skin Associated with Parasite Density in Canine Visceral Leishmaniasis

摘要

BackgroundThe immune response in the skin of dogs infected with Leishmania infantum is poorly understood, and limited studies have described the immunopathological profile with regard to distinct levels of tissue parasitism and the clinical progression of canine visceral leishmaniasis (CVL).