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Vasoactive Intestinal Polypeptide and Mast Cells Regulate Increased Passage of Colonic Bacteria in Patients With Irritable Bowel Syndrome

机译：肠易激综合征患者血管活性肠多肽和肥大细胞调节结肠细菌的通过增加

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Background & AimsIrritable bowel syndrome (IBS) is associated with intestinal dysbiosis and symptoms of IBS develop following gastroenteritis. We aimed to study passage of live bacteria through the colonic epithelium, and determine the role of mast cells and vasoactive intestinal polypeptide (VIP) in barrier regulation in IBS and healthy individuals.

机译：背景与目的肠易激综合症（IBS）与肠营养不良有关，肠胃炎后IBS的症状发展。我们旨在研究活细菌通过结肠上皮的传播，并确定肥大细胞和血管活性肠多肽（VIP）在IBS和健康个体的屏障调节中的作用。

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期刊名称 other
作者
Olga Bednarska; Susanna A Walter; Maite Casado-Bedmar; Magnus Ström; Eloísa Salvo-Romero; Maria Vicario; Emeran A Mayer; Åsa V Keita;
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年(卷),期 -1(153),4
年度 -1
页码 e3
总页数 24
原文格式 PDF
正文语种
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关键词
Intestinal permeability bacteria ketotifen inflammation;

机译：肠道通透性;细菌;酮替芬;炎症;

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专利

1. Vasoactive Intestinal Polypeptide and Mast Cells Regulate Increased Passage of Colonic Bacteria in Patients With Irritable Bowel Syndrome [J] . Bednarska Olga, Walter Susanna A., Casado-Bedmar Maite, Gastroenterology . 2017 ,第4期

机译：血管活性肠多肽和肥大细胞调节肠易肠综合征患者结肠细菌的增加
2. Mast cells are increased in the small intestinal mucosa of patients with irritable bowel syndrome: A systematic review and meta‐analysis [J] . Robles Alejandro, Perez Ingles David, Myneedu Kanchana, Neurogastroenterology and motility . 2019 ,第12期

机译：在肠肠综合征患者的小肠粘膜中增加了肥大细胞：系统审查和荟萃分析
3. Serum Exosomes Derived from Irritable Bowel Syndrome Patient Increase Cell Permeability via Regulating miR-148b-5p/RGS2 Signaling in Human Colonic Epithelium Cells [J] . Ying Xing, Shan Xue, Jing Wu, Gastroenterology research and practice . 2021 ,第a期

机译：来自肠辨别综合征患者的血清外泌体通过调节人性结肠上皮细胞中的miR-148b-5p / Rgs2信号来增加细胞渗透性
4. The Effects of Wumei Pill on Intestinal Flora and Neurotransmitters in Rats with Diarrhea-predominant Irritable Bowel Syndrome (IBS-D) [C] . Xiaojie Ding, Xiling Sun, Xiaofei Yu, International Conference on Biotechnology and Bioengineering . 2019

机译：尿布丸对腹泻的肠道菌群和神经递质的影响（IBS-D）
5. Biological effects of vasoactive intestinal peptide/pituitary adenylate cyclase activating polypeptide receptor 1 (VPAC1) and VPAC2 on chemotaxis and its regulation of the tumor suppressor Ikaros in leukemic T cells. [D] . Van der Steen, Travis. 2012

机译：血管活性肠肽/垂体腺苷酸环化酶激活多肽受体1（VPAC1）和VPAC2的生物学效应对白血病T细胞的趋化性及其对肿瘤抑制因子Ikaros的调节。
6. Serum Exosomes Derived from Irritable Bowel Syndrome Patient Increase Cell Permeability via Regulating miR-148b-5p/RGS2 Signaling in Human Colonic Epithelium Cells [O] . Ying Xing, Shan Xue, Jing Wu, 2021

机译：来自肠辨别综合征患者的血清外泌体通过调节人性结肠上皮细胞中的miR-148b-5p / Rgs2信号来增加细胞渗透性
7. INCREASES IN ILEAL MAST CELLS IN PATIENTS WITH DIARRHOEA PREDOMINANT IRRITABLE BOWEL SYNDROME MAY BE DUE TO A RELATIVE REDUCTION IN MUCOSA-ASSOCIATED LACTOBACILLI [O] . Parkes, G. C., Rayment, N., Woodman, I., 2011

机译：腹泻型主要肠易激综合征患者的乳腺肥大细胞增加可能是由于黏膜相关乳杆菌的相对减少

Vasoactive Intestinal Polypeptide and Mast Cells Regulate Increased Passage of Colonic Bacteria in Patients With Irritable Bowel Syndrome

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