Antiarrhythmic Drugs for Non-shockable-Turned-Shockable Out-of-Hospital Cardiac Arrest: The Amiodarone Lidocaine or Placebo Study (ALPS)

摘要

BackgroundOut-of-hospital cardiac arrest (OHCA) commonly presents with non-shockable rhythms (asystole and pulseless electrical activity (PEA)). Whether antiarrhythmic drugs are safe and effective when these evolve to shockable rhythms (ventricular fibrillation/pulseless ventricular tachycardia (VF/VT)) during resuscitation is not known.