Cross-phenotype analysis of Immunochip data identifies KDM4C as arelevant locus for the development of systemic vasculitis

摘要

ObjetiveSystemic vasculitides represent a heterogeneous group of rare complex diseases of the blood vessels with a poorly understood aetiology. To investigate the shared genetic component underlying their predisposition, we performed the first cross-phenotype meta-analysis of genetic data from different clinically distinct patterns of vasculitis.