Filter-Probe Diffusion Imaging Improves Spinal Cord Injury Outcome Prediction

摘要

ObjectiveDiffusion weighted imaging (DWI) is a powerful tool for investigating spinal cord injury (SCI), but has limited specificity for axonal damage- the most predictive feature of long-term functional outcome. In this study, a technique designed to detect acute axonal injury, filter-probe double diffusion encoding (FP-DDE) is compared with standard DWI for predicting long-term functional and cellular outcomes.