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Effect of In Utero Hydroxychloroquine Exposure on the Development of Cutaneous Neonatal Lupus Erythematosus

机译：子宫内羟氯喹暴露对新生儿皮肤红斑狼疮发展的影响

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摘要

Objective:Cutaneous neonatal lupus (cNL) occurs in possibly 5-16% of anti-Ro±anti-La antibody exposed infants. Data suggest in utero exposure to hydroxychloroquine (HCQ) may prevent cardiac-NL. The aims were to assess whether in utero exposure to HCQ decreases the risk of cNL and/or delays onset.

机译：目的：在暴露于抗Ro±anti-La抗体的婴儿中，可能出现5-16％的新生儿新生儿狼疮（cNL）。数据表明子宫内暴露于羟氯喹（HCQ）可能会预防心脏-NL。目的是评估子宫内接触HCQ是否会降低cNL和/或延迟发作的风险。

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期刊名称 other
作者
Julie Barsalou; Nathalie Costedoat-Chalumeau; Adey Berhanu; Cesar Fors-Nieves; Ummara Shah; Patrick Brown; Carl A. Laskin; Nathalie Morel; Kateri Levesque; Jill P. Buyon; Earl D. Silverman; Peter M. Izmirly;
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年(卷),期 -1(77),12
年度 -1
页码 1742–1749
总页数 21
原文格式 PDF
正文语种
中图分类
关键词
Neonatal lupus cutaneous neonatal lupus hydroxychlororquine pregnancy;

机译：新生儿狼疮;皮肤性新生儿狼疮;羟氯喹;怀孕;

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专利

1. Effect of in utero hydroxychloroquine exposure on the development of cutaneous neonatal lupus erythematosus [J] . Barsalou Julie, Costedoat-Chalumeau Nathalie, Berhanu Adey, Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research . 2018,第12期

机译：羟基氯喹暴露对皮肤新生儿红斑狼疮发育的影响
2. Response to hydroxychloroquine in Japanese patients with systemic lupus erythematosus using the cutaneous lupus erythematosus disease area and severity index (CLASI) [J] . Naoto Yokogawa, Yukihiko Kato, Shoji Sugii, Modern Rheumatology . 2012,第2期

机译：日本人系统性红斑狼疮对羟氯喹的反应，使用皮肤性红斑狼疮的疾病面积和严重程度指数（CLASI）
3. Response to hydroxychloroquine in Japanese patients with systemic lupus erythematosus using the cutaneous lupus erythematosus disease area and severity index (CLASI) [J] . YokogawaN., KatoY., SugiiS., Modern rheumatology . 2012,第2期

机译：日本人系统性红斑狼疮对羟氯喹的反应，使用皮肤性红斑狼疮的疾病面积和严重程度指数（CLASI）
4. Utility of polarized dermoscopy in the diagnosis of cutaneous lupus erythematosus and morphea [C] . Mihaela Paula Toader, Irina Mihaela Esanu, Tatiana Taranu, 2017 E-Health and Bioengineering Conference . 2017

机译：偏振皮肤镜检查在诊断皮肤红斑狼疮和吗啡中的用途
5. Occupational exposure to crystalline silica and the development of systemic lupus erythematosus (SLE): A case-control study in the southeastern United States. [D] . Parks, Christine Gibson. 2001

机译：职业接触结晶二氧化硅和系统性红斑狼疮（SLE）的发展：美国东南部的病例对照研究。
6. Exfoliative cutaneous lupus erythematosus in German shorthaired pointer dogs: disease development progression and evaluation of three immunomodulatory drugs (ciclosporin hydroxychloroquine and adalimumab) in a controlled environment [O] . Elizabeth A. Mauldin, Daniel O. Morris, Dorothy C. Brown, -1

机译：剥脱皮肤型红斑狼疮的德国短毛犬指针：疾病的发展在受控环境中发展和三种免疫调节药物（环孢素羟氯喹和阿达木单抗）评价
7. Exfoliative cutaneous lupus erythematosus in German shorthaired pointer dogs: disease development, progression and evaluation of three immunomodulatory drugs (ciclosporin, hydroxychloroquine, and adalimumab) in a controlled environment [O] . Elizabeth A. Mauldin, Daniel O. Morris, Dorothy C. Brown, 2010

机译：德国矮小指针犬的抗抗皮肤皮肤红斑狼疮：在受控环境中疾病开发，进展和评价三种免疫调节药物（Ciclosporin，羟氯喹和atabalimalab）

Effect of In Utero Hydroxychloroquine Exposure on the Development of Cutaneous Neonatal Lupus Erythematosus

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