The association of headache frequency with pain interference and the burden of disease is mediated by depression and sleep quality but not anxiety in chronic tension type headache

摘要

BackgroundA better understanding of potential relationship between mood disorders, sleep quality, pain, and headache frequency may assist clinicians in determining optimal therapeutic programs. The aim of the current study was to analyze the effects of sleep quality, anxiety, depression on potential relationships between headache intensity, burden of headache, and headache frequency in chronic tension type headache (CTTH).