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Integrated Mental Health Services for the Developmental Period (0 to 25 Years): A Critical Review of the Evidence

机译:发育期(0至25年)的综合精神卫生服务:证据的严格审查

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摘要

>Background: The developmental period from 0 to 25 years is a vulnerable time during which children and young people experience many psychosocial and neurobiological changes and an increased incidence of mental illness. New clinical services for children and young people aged 0 to 25 years may represent a radical transformation of mental healthcare. >Method: Critical, non-systematic review of the PubMed literature up to 3rd January 2019. >Results: Rationale: the youngest age group has an increased risk of developing mental disorders and 75% of mental disorders begin by the age of 24 and prodromal features may start even earlier. Most of the risk factors for mental disorders exert their role before the age of 25, profound maturational brain changes occur from mid-childhood through puberty to the mid-20s, and mental disorders that persist in adulthood have poor long-term outcomes. The optimal window of opportunity to improve the outcomes of mental disorders is the prevention or early treatment in individuals aged 0 to 25 within a clinical staging model framework. Unmet needs: children and young people face barriers to primary and secondary care access, delays in receiving appropriate treatments, poor engagement, cracks between child and adult mental health services, poor involvement in the design of mental health services, and lack of evidence-based treatments. Evidence: the most established paradigm for reforming youth mental services focuses on people aged 12–25 who experienced early stages of psychosis. Future advancements may include early stages of depression and bipolar disorders. Broader youth mental health services have been implemented worldwide, but no single example constitutes best practice. These services seem to improve access, symptomatic and functional outcomes, and satisfaction of children and young people aged 12–25. However, there are no robust controlled trials demonstrating their impact. Very limited evidence is available for integrated mental health services that focus on people aged 0–12. >Conclusions: Children and young people aged 12–25 need youth-friendly mental health services that are sensitive to their unique stage of clinical, neurobiological, and psychosocial development. Early intervention for psychosis services may represent the starting platform to refine the next generation of integrated youth mental health services.
机译:>背景:从0到25岁的发育期是一个脆弱的时期,在此期间,儿童和年轻人会经历许多社会心理和神经生物学变化,并增加精神疾病的发病率。为0至25岁的儿童和年轻人提供的新临床服务可能代表着精神保健的根本转变。 >方法:截止至2019年1月3日,对PubMed文献进行了重要的非系统性评论。>结果:理由:年龄最小的人群患精神障碍的风险增加,年龄为75岁%的精神障碍由24岁开始,并且前驱特征可能更早开始。精神障碍的大多数危险因素在25岁之前发挥作用,从童年中期到青春期到20年代中期,大脑发生了成熟的深刻变化,成年后持续存在的精神障碍的长期预后较差。改善精神障碍预后的最佳机会是在临床分期模型框架内预防或早期治疗0至25岁的人。需求未得到满足:儿童和年轻人在获得初级和二级医疗服务方面面临障碍,延迟接受适当的治疗,参与度差,儿童和成人精神卫生服务之间的裂痕,精神卫生服务设计的参与不足以及缺乏循证医学治疗。证据:改革青年精神服务的最成熟范例集中于经历过精神病早期阶段的12-25岁人群。未来的发展可能包括抑郁症和躁郁症的早期阶段。在世界范围内已经实施了更广泛的青年精神卫生服务,但是没有一个单独的例子可以构成最佳实践。这些服务似乎可以改善12-25岁儿童和年轻人的获得机会,症状和功能结局以及满意度。但是,尚无可靠的对照试验证明其影响。对于以0至12岁的人群为重点的综合精神卫生服务的可用证据非常有限。 >结论: 12至25岁的儿童和年轻人需要对青少年友善的心理健康服务,这些服务对其临床,神经生物学和社会心理发展的独特阶段敏感。对精神病服务的早期干预可能是完善下一代综合青年精神卫生服务的起始平台。

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