An acceptability and safety study of the Duet® cervical barrier and gel delivery system in Zimbabwe

摘要

BackgroundAdherence problems with coitally dependent, female-initiated HIV prevention methods have contributed to several trials' failure to establish efficacy. Continuous use of a cervical barrier with once-daily cleaning and immediate reinsertion may simplify use for women and improve adherence. We assessed the acceptability and safety of precoital and continuous use of the Duet^®, a cervical barrier and gel delivery system, in Zimbabwean women.