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Tyrosine kinase inhibitor discontinuation in patients with chronic myeloid leukemia: a single-institution experience

机译：慢性粒细胞白血病患者停用酪氨酸激酶抑制剂的单机构经验

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BackgroundPatients with CML treated with TKI can have a life expectancy comparable to that of the general population. Due to the extended duration of TKI administration, treatment discontinuation has been increasingly sought.

机译：背景接受TKI治疗的CML患者的预期寿命可与普通人群相比。由于TKI施用的持续时间延长，因此越来越寻求中止治疗。

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期刊名称 Journal of Hematology Oncology
作者
Kamal Chamoun; Hagop Kantarjian; Rami Atallah; Graciela Nogueras Gonzalez; Ghayas C. Issa; Mary Beth Rios; Guillermo Garcia-Manero; Gautam Borthakur; Farhad Ravandi; Nitin Jain; Naval Daver; Marina Konopleva; Courtney D. DiNardo; Tapan Kadia; Naveen Pemmaraju; Elias Jabbour; Jorge Cortes;
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作者单位

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年(卷),期 2019(12),-1
年度 2019
页码 1
总页数 10
原文格式 PDF
正文语种
中图分类肿瘤学;血液学检验;
关键词
CML TKI discontinuation MRsup4.5/sup;

机译：CML;TKI停产;MR sup 4.5 / sup;

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专利

1. Tyrosine kinase inhibitor discontinuation in patients with chronic myeloid leukemia: a single-institution experience [J] . Kamal Chamoun, Hagop Kantarjian, Rami Atallah, Journal of Hematology and Oncology . 2019,第1期

机译：慢性髓细胞性白血病患者停用酪氨酸激酶抑制剂的单一机构经验
2. Outcomes of unplanned tyrosine kinase inhibitor discontinuation in patients with chronic myeloid leukemia: retrospective analysis of real-world experience in a single institution [J] . Masaki Iino, Takeo Yamamoto, Yuma Sakamoto Hematology . 2019,第1期

机译：慢性骨髓白血病患者的无计划酪氨酸激酶抑制剂的结果：回顾性分析了一个机构的现实世界经验
3. Adherence and future discontinuation of tyrosine kinase inhibitors in chronic phase chronic myeloid leukemia. A patient- based survey on 1133 patients [J] . Breccia Massimo, Efficace Fabio, Sica Simona, Leukemia Research: A Forum for Studies on Leukemia and Normal Hemopoiesis . 2015,第10期

机译：慢性期慢性粒细胞白血病中酪氨酸激酶抑制剂的依从性和未来的停用。对1133名患者进行的基于患者的调查
4. Novel Inhibitors of T315I Mutant BCR-ABL1 Tyrosine Kinase for Chronic Myeloid Leukemia Disease Through Fragment-Based Drug Design [C] . Satya Anindita, Atika Marnolia, Hersal Hermana Putra, International symposium on bioinformatics research and applications . 2018

机译：T315I突变BCR-ABL1酪氨酸激酶的新型抑制剂通过基于片段的药物设计治疗慢性粒细胞白血病
5. The multi-targeted receptor tyrosine kinase inhibitor, linifanib (ABT-869), induces apoptosis and inhibits proliferation of leukemia cells through phosphoinositide-3 kinase (PI3K)/AKT-dependent signaling pathways. [D] . Hernandez, Jenny Elizabeth. 2010

机译：多靶点受体酪氨酸激酶抑制剂利尼法尼（ABT-869）通过磷酸肌醇3激酶（PI3K）/ AKT依赖性信号传导途径诱导凋亡并抑制白血病细胞的增殖。
6. Tyrosine kinase inhibitor interruptions discontinuations and switching in patients with chronic‐phase chronic myeloid leukemia in routine clinical practice: SIMPLICITY [O] . Rüdiger Hehlmann, Jorge E. Cortes, Teresa Zyczynski, -1

机译：常规临床实践中的慢性阶段性慢性粒细胞白血病患者酪氨酸激酶抑制剂的中断停药和转换：简单
7. Adherence and future discontinuation of tyrosine kinase inhibitors in chronic phase chronic myeloid leukemia. A patient-based survey on 1133 patients [O] . Breccia Massimo, Efficace Fabio, Sica Simona, 2015

机译：慢性期慢性粒细胞白血病中酪氨酸激酶抑制剂的依从性和未来的停用。对1133名患者进行的基于患者的调查

Tyrosine kinase inhibitor discontinuation in patients with chronic myeloid leukemia: a single-institution experience

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