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Long noncoding RNA NEAT1 regulates the development of osteosarcoma through sponging miR‐34a‐5p to mediate HOXA13 expression as a competitive endogenous RNA

机译：较长的非编码RNA NEAT1通过使miR‐34a‐5p海绵化来调节HOXA13的表达使其成为竞争性内源性RNA从而调节骨肉瘤的发育

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BackgroundLong noncoding RNA (lncRNA) exerts a potential regulatory role in tumorigenesis. LncRNA NEAT1 expression remains high in osteosarcoma tissues. However, its biological mechanism in osteosarcoma remains unknown.

机译：背景长非编码RNA（lncRNA）在肿瘤发生中发挥潜在的调控作用。 LncRNA NEAT1在骨肉瘤组织中的表达仍然很高。然而，其在骨肉瘤中的生物学机制仍然未知。

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期刊名称 Molecular Genetics Genomic Medicine
作者
Shaolin Ji; Shunsheng Wang; Xiaodan Zhao; Li Lv;
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作者单位

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年(卷),期 2019(7),6
年度 2019
页码 e673
总页数 9
原文格式 PDF
正文语种
中图分类遗传学;
关键词
apoptosis long noncoding RNA osteosarcoma proliferation;

机译：凋亡;长非编码RNA;骨肉瘤;增殖;

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专利

1. Long noncoding RNA NEAT1 regulates the development of osteosarcoma through sponging miR‐34a‐5p to mediate HOXA13 expression as a competitive endogenous RNA [J] . Shaolin Ji, Shunsheng Wang, Xiaodan Zhao, Molecular Genetics & Genomic Medicine . 2019,第6期

机译：长度非编码RNA Neat1通过海绵miR-34a-5p调节骨肉瘤的发育，将Hoxa13表达介导作为竞争内源性RNA
2. Long noncoding RNA CCAT2 functions as a competitive endogenous RNA to regulate FOXC1 expression by sponging miR‐23b‐5p in lung adenocarcinoma [J] . Hu Guo‐dong, Wang Cheng‐xiang, Wang Hong‐ying, Journal of cellular biochemistry. . 2019,第5期

机译：长度非编码RNA CCAT2用作竞争内源性RNA，以通过在肺腺癌中的miR-23b-5p冲压miR-23b-5p来调节foxc1表达
3. Long noncoding RNA MALAT1 regulates HDAC4‐mediated proliferation and apoptosis via decoying of miR‐140‐5p in osteosarcoma cells [J] . Yuxiu Sun, Baoli Qin Cancer Medicine . 2018,第9期

机译：较长的非编码RNA MALAT1通过在骨肉瘤细胞中诱变miR‐140-5p来调节HDAC4介导的增殖和凋亡
4. Predicted Regulatory Pathways for Long Noncoding RNA-SNHG7 via miR-34a and its Targets in Alzheimer’s Disease [C] . Jian Shi IEEE International Conference on Bioinformatics and Biomedicine . 2020

机译：通过miR-34a预测长度非编码RNA-snhg7的调节途径及其在阿尔茨海默病的靶标
5. A conditional microrna sponge transgene reveals a role for the microrna miR-7 in cortical neurogenesis. [D] . Pollock, Andrew Morris Solomon. 2014

机译：有条件的microrna海绵转基因揭示了microrna miR-7在皮层神经发生中的作用。
6. Long noncoding RNA MALAT1 regulates HDAC4‐mediated proliferation and apoptosis via decoying of miR‐140‐5p in osteosarcoma cells [O] . Yuxiu Sun, Baoli Qin 2018

机译：较长的非编码RNA MALAT1通过在骨肉瘤细胞中诱变miR‐140-5p来调节HDAC4介导的增殖和凋亡
7. Long noncoding RNA NEAT1 regulates the development of osteosarcoma through sponging miR‐34a‐5p to mediate HOXA13 expression as a competitive endogenous RNA [O] . Shaolin Ji, Shunsheng Wang, Xiaodan Zhao, 2019

机译：长度非编码RNA Neat1通过海绵miR-34a-5p调节骨肉瘤的发育，将Hoxa13表达介导作为竞争内源性RNA

Long noncoding RNA NEAT1 regulates the development of osteosarcoma through sponging miR‐34a‐5p to mediate HOXA13 expression as a competitive endogenous RNA

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