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A computational fluid–structure interaction model to predict the biomechanical properties of the artificial functionally graded aorta

机译:计算流体-结构相互作用模型用于预测人工功能梯度主动脉的生物力学特性

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摘要

In the present study, three layers of the ascending aorta in respect to the time and space at various blood pressures have been simulated. Two well-known commercial finite element (FE) software have used to be able to provide a range of reliable numerical results while independent on the software type. The radial displacement compared with the time as well as the peripheral stress and von Mises stress of the aorta have calculated. The aorta model was validated using the differential quadrature method (DQM) solution and, then, in order to design functionally graded materials (FGMs) with different heterogeneous indexes for the artificial vessel, two different materials have been employed. Fluid–structure interaction (FSI) simulation has been carried out on the FGM and a natural vessel of the human body. The heterogeneous index defines the variation of the length in a function. The blood pressure was considered to be a function of both the time and location. Finally, the response characteristics of functionally graded biomaterials (FGBMs) models with different values of heterogeneous material parameters were determined and compared with the behaviour of a natural vessel. The results showed a very good agreement between the numerical findings of the FGM materials and that of the natural vessel. The findings of the present study may have implications not only to understand the performance of different FGMs in bearing the stress and deformation in comparison with the natural human vessels, but also to provide information for the biomaterials expert to be able to select a suitable material as an implant for the aorta.
机译:在本研究中,在不同血压下,关于时间和空间的升主动脉分为三层。两种众所周知的商业有限元(FE)软件已能够在不依赖于软件类型的情况下提供一系列可靠的数值结果。计算了与时间相比的径向位移以及主动脉的周边应力和von Mises应力。使用差分正交方法(DQM)解决方案验证了主动脉模型,然后,为了设计人造血管具有不同异质性指标的功能梯度材料(FGM),已使用了两种不同的材料。在FGM和人体的天然血管上进行了流固耦合(FSI)模拟。异类索引定义函数中长度的变化。血压被认为是时间和位置的函数。最后,确定了功能梯度生物材料(FGBMs)模型具有不同的异质材料参数值的响应特性,并将其与天然血管的行为进行了比较。结果表明,FGM材料的数值结果与天然容器的数值结果非常吻合。本研究的发现可能不仅有助于理解不同的女性生殖器官与自然人血管相比在承受压力和变形方面的性能,而且还可以为生物材料专家提供信息以选择合适的材料作为参考。主动脉植入物。

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