首页> 美国卫生研究院文献>Journal of Korean Medical Science >Percutaneous Coronary Intervention versus Coronary Artery Bypass Grafting for Diabetics with Multivessel Coronary Artery Disease: The Korean Multicenter Revascularization Registry (KORR)
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Percutaneous Coronary Intervention versus Coronary Artery Bypass Grafting for Diabetics with Multivessel Coronary Artery Disease: The Korean Multicenter Revascularization Registry (KORR)

机译:糖尿病合并多支血管冠状动脉疾病的经皮冠状动脉介入治疗与冠状动脉旁路移植术:韩国多中心血运重建术(KORR)

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摘要

This study was designed to assess the relative merits of percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) in multivessel coronary artery disease (MVCAD), particularly for Korean diabetics. Among 3,279 patients with MVCAD who were recommended for revascularization were enrolled from nine centers in Korea, 2,154 were selected after statistical adjustments for the disparities between two groups. Survival rates were not significantly different for three years between two groups. Among diabetic patients, the three-year mortality rate in PCI group was 1.9-fold higher than that of CABG group, although it was not statistically significant (PCI 19.8%, CABG 11.4%, p=0.14). The three-year mortality rate was similar between the two groups in non-diabetics (PCI 8.3%, CABG 10.0%, p=0.50). The 30-day rate of cerebrovascular event was higher in CABG group, for both diabetic (CABG 3.6%, PCI 0.0%, p<0.001) and non-diabetic patients (CABG 2.4%, PCI 0.0%, p<0.001). Short- and long-term revascularization rates were higher in PCI group than in CABG group. As a conclusion, this Korean registry demonstrates that PCI was associated with comparable survival rates and lower short-term morbidity, but a greater requirement for repeated revascularization compared with CABG in Korean diabetics.
机译:本研究旨在评估经皮冠状动脉介入治疗(PCI)和冠状动脉旁路移植术(CABG)在多支冠状动脉疾病(MVCAD)中的相对优势,尤其是对于韩国糖尿病患者。在韩国9个中心的3279例被推荐进行血管重建的MVCAD患者中,对两组之间的差异进行统计学调整后,选择了2154例。两组之间三年的存活率没有显着差异。在糖尿病患者中,PCI组的三年死亡率比CABG组高1.9倍,尽管无统计学意义(PCI 19.8%,CABG 11.4%,p = 0.14)。两组非糖尿病患者的三年死亡率相似(PCI 8.3%,CABG 10.0%,p = 0.50)。对于糖尿病患者(CABG 3.6%,PCI 0.0%,p <0.001)和非糖尿病患者(CABG 2.4%,PCI 0.0%,p <0.001),CABG组的30天脑血管事件发生率均较高。 PCI组的短期和长期血运重建率高于CABG组。作为结论,该韩国注册研究表明,与韩国糖尿病患者相比,CABG与PCI的生存率较高,短期发病率较低相关,但与CABG相比,重复血运重建的要求更高。

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