Aberrant functional connectivity density in patients with treatment-refractory obsessive-compulsive disorder: a pilot study

摘要

ObjectiveFunctional connectivity (FC) is altered in patients with obsessive-compulsive disorder (OCD). Most previous studies have focused on the strength of FC in patients with OCD; few have examined the number of functional connections in these patients. The number of functional connections is an important index for assessing aberrant FC. In the present study, we used FC density (FCD) mapping to explore alterations in the number of functional connections in patients with treatment-refractory OCD (TROCD) using the FCD index.