Comparison of hospital-wide and age and location - stratified antibiograms of S. aureus E. coli and S. pneumoniae: age- and location-stratified antibiograms

摘要

BackgroundAntibiograms created by aggregating hospital-wide susceptibility data from diverse patients can be misleading. To demonstrate the utility of age- and location-stratified antibiograms, we compared stratified antibiograms for three common bacterial pathogens, E. coli, S. aureus, and S. pneumoniae. We created stratified antibiograms based on patient age (<18 years, 18–64 years, >/=65 years), and inpatient or outpatient location using all 2009 E. coli and S. aureus, and all 2008–2009 S. pneumoniae isolates submitted to our clinical microbiology laboratory. We compared susceptibility rates among cumulative and stratified antibiograms using descriptive statistics.