Agnostic Pathway/Gene Set Analysis of Genome-Wide Association Data Identifies Associations for Pancreatic Cancer

机译：全基因组关联数据的不可知途径/基因组分析确定了胰腺癌的关联

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BackgroundGenome-wide association studies (GWAS) identify associations of individual single-nucleotide polymorphisms (SNPs) with cancer risk but usually only explain a fraction of the inherited variability. Pathway analysis of genetic variants is a powerful tool to identify networks of susceptibility genes.

机译：背景全基因组关联研究（GWAS）确定了单个单核苷酸多态性（SNP）与癌症风险的关联，但通常仅解释了遗传变异的一小部分。遗传变异的途径分析是鉴定易感基因网络的有力工具。

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1. Agnostic Pathway/Gene Set Analysis of Genome-Wide Association Data Identifies Associations for Pancreatic Cancer [J] . Walsh Naomi, Zhang Han, Hyland Paula L., Journal of the National Cancer Institute . 2019,第6期

机译：易毒性途径/基因集分析基因组关联数据识别胰腺癌的关联
2. Pathway analysis of genome-wide association study data highlights pancreatic development genes as susceptibility factors for pancreatic cancer [J] . Donghui Li, Eric J. Duell, Kai Yu, Carcinogenesis . 2012,第7期

机译：全基因组关联研究数据的途径分析突出了胰腺发育基因作为胰腺癌的易感因素
3. Pathway analysis of genome-wide association study data highlights pancreatic development genes as susceptibility factors for pancreatic cancer [J] . Donghui Li†‡ Eric J. Duell1†‡ Kai Yu2†‡ Harvey A. Risch3‡ Sara H. Olson4‡ Charles Kooperberg5‡ Brian M. Wolpin67‡ Li Jiao8‡ Xiaoqun Dong‡ Bill Wheeler9‡ Alan A. Arslan101112 H. Bas Bueno-de-Mesquita1314 Charles S. Fuchs67 Steven Gallinger15 Myron Gross16 Patricia Hartge2 Robert N. Hoover2 Elizabeth A. Holly17 Eric J. Jacobs18 Alison P. Klein1920 Andrea LaCroix5 Margaret T. Mandelson521 Gloria Petersen22 Wei Zheng23 Ilir Agalliu24 Demetrius Albanes2 Marie-Christine Boutron-Ruault25 Paige M. Bracci17 Julie E. Buring2627 Federico Canzian28 Kenneth Chang29 Stephen J. Chanock23031 Michelle Cotterchio3233 J.Michael Gaziano34 Edward L. Giovannucci73536 Michael Goggins37 Göran Hallmans38 Susan E. Hankinson735 Judith A. Hoffman Bolton39 David J. Hunter735 Amy Hutchinson231 Kevin B. Jacobs23140 Mazda Jenab41 Kay-Tee Khaw42 P Carcinogenesis . 2012,第7期

机译：全基因组关联研究数据的途径分析突出了胰腺发育基因作为胰腺癌的易感因素
4. GENOME-WIDE ASSOCIATION ANALYSIS IDENTIFIES A MAJOR GENE FOR LATE MATURITY ALPHA-AMYLASE (LMA) ACTIVITY IN SYNTHETICHEXAPLOID WHEAT [C] . L.C. Emebiri, J.R. Oliver, K. Mrva, Australian cereal chemistry conference . 2010

机译：基因组 - 宽的关联分析鉴定了合成素薄液中晚期成熟α-淀粉酶（LMA）活性的主要基因
5. Pancreatic cancer risk and prevention: Association with PPARG gene and policy analysis of tobacco-related pancreatic cancer. [D] . Fesinmeyer, Megan Dann. 2007

机译：胰腺癌的风险和预防：与PPARG基因的关联以及与烟草有关的胰腺癌的政策分析。
6. Pathway analysis of genome-wide association study data highlights pancreatic development genes as susceptibility factors for pancreatic cancer [O] . Donghui Li, Eric J. Duell, Kai Yu, -1

机译：全基因组关联研究数据的途径分析突出了胰腺发育基因作为胰腺癌的易感因素
7. Agnostic Pathway/Gene Set Analysis of Genome-Wide Association Data Identifies Associations for Pancreatic Cancer [O] . Naomi Walsh, Han Zhang, Paula L Hyland, 2018

机译：易毒性途径/基因集分析基因组关联数据识别胰腺癌的关联

Agnostic Pathway/Gene Set Analysis of Genome-Wide Association Data Identifies Associations for Pancreatic Cancer

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