Heritability of and Mortality Prediction With a Longevity Phenotype: The Healthy Aging Index

机译：长寿表型的遗传力和死亡率预测：健康老龄化指数

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Background.Longevity-associated genes may modulate risk for age-related diseases and survival. The Healthy Aging Index (HAI) may be a subphenotype of longevity, which can be constructed in many studies for genetic analysis. We investigated the HAI’s association with survival in the Cardiovascular Health Study and heritability in the Long Life Family Study.

机译：背景：与寿命相关的基因可能会调节与年龄有关的疾病和生存的风险。健康衰老指数（HAI）可能是寿命的一个亚型，可以在许多研究中进行遗传分析。我们调查了HAI与心血管健康研究中的生存率以及长寿家庭研究中的遗传力之间的关系。

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期刊名称 The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
作者
Jason L. Sanders; Ryan L. Minster; M. Michael Barmada; Amy M. Matteini; Robert M. Boudreau; Kaare Christensen; Richard Mayeux; Ingrid B. Borecki; Qunyuan Zhang; Thomas Perls; Anne B. Newman;
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年(卷),期 -1(69),4
年度 -1
页码 479–485
总页数 7
原文格式 PDF
正文语种
中图分类老年病学;老年卫生;
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专利

1. Heritability of and Mortality Prediction With a Longevity Phenotype: The Healthy Aging Index [J] . Jason L. Sers, Ryan L. Minster, M. Michael Barmada, The journals of gerontology.Series A. Biological sciences and medical sciences . 2014,第4期

机译：长寿表型的遗传力和死亡率预测：健康老龄化指数
2. Is Longevity a Heritable Trait? Evidence for Non-genomic Influence from an Extended Longevity Phenotype of Drosophila melanogaster [J] . S. Deepashree, T. Shivanandappa, S.R. Ramesh Current aging science . 2018,第1期

机译：是长寿是一个可遗传的特质吗？来自果蝇黑素糖蛋白酶的延长寿命表型的非基因组影响的证据
3. Frailty phenotype, frailty index and risk of mortality in Chinese elderly population- Rugao longevity and ageing study [J] . Shi Guo-Ping, Ma Teng, Zhu Yin-Sheng, Archives of Gerontology and Geriatrics: An International Journal Integrating Experimental, Clinical and Social Studies on Ageing . 2019,第期

机译：中国老年人人口长寿和老化研究中的脆弱表型，体力指数和死亡率风险
4. All-Cause Mortality Risks Associated with Long-Term Exposure to Ambient Fine Particulate Matter in the Chinese Healthy Longevity Cohort [C] . Tiantian Li, Yi Zhang, Jiaonan Wang, Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology . 2018

机译：与中国健康长寿人群长期接触环境细颗粒物相关的全因死亡率风险
5. Understanding the determinants of aging and longevity: The influence of the social environment, biology, and heritability throughout the life course [D] . Hanson, Heidi Anne 2013

机译：了解衰老和长寿的决定因素：一生中社会环境，生物学和遗传力的影响
6. Self‐Reported Cardiorespiratory Fitness: Prediction and Classification of Risk of Cardiovascular Disease Mortality and Longevity—A Prospective Investigation in the Copenhagen City Heart Study [O] . Andreas Holtermann, Jacob Louis Marott, Finn Gyntelberg, 2015

机译：自我报告的心脏呼吸适应性：心血管疾病死亡率和长寿风险的预测和分类-哥本哈根市心脏研究的一项前瞻性研究
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Heritability of and Mortality Prediction With a Longevity Phenotype: The Healthy Aging Index

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