首页> 美国卫生研究院文献>Journal of Clinical Oncology >Pediatric Phase I and Pharmacokinetic Study of Erlotinib Followed by the Combination of Erlotinib and Temozolomide: A Childrens Oncology Group Phase I Consortium Study

【2h】

Pediatric Phase I and Pharmacokinetic Study of Erlotinib Followed by the Combination of Erlotinib and Temozolomide: A Childrens Oncology Group Phase I Consortium Study

机译：厄洛替尼的儿科I期和药代动力学研究随后厄洛替尼与替莫唑胺合用：儿童肿瘤学组I期联合研究

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

PurposeWe conducted a phase I and pharmacokinetic study of the epidermal growth factor receptor (EGFR) inhibitor erlotinib as a single agent and in combination with temozolomide in children with refractory solid tumors.

机译：目的我们对表皮生长因子受体（EGFR）抑制剂厄洛替尼作为单一药物并与替莫唑胺联用治疗难治性实体瘤儿童进行了I期和药代动力学研究。

著录项

期刊名称 Journal of Clinical Oncology
作者
Regina I. Jakacki; Marta Hamilton; Richard J. Gilbertson; Susan M. Blaney; Jean Tersak; Mark D. Krailo; Ashish M. Ingle; Stephan D. Voss; Janet E. Dancey; Peter C. Adamson;
展开▼
作者单位

展开▼
年(卷),期 -1(26),30
年度 -1
页码 4921–4927
总页数 7
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词

相似文献

外文文献
中文文献
专利

1. Pediatric phase I and pharmacokinetic study of erlotinib followed by the combination of erlotinib and temozolomide: a Children's Oncology Group Phase I Consortium Study. [J] . Jakacki RI, Hamilton M, Gilbertson RJ, Journal of Clinical Oncology . 2008,第30期

机译：儿科I期和厄洛替尼的药代动力学研究，然后联合厄洛替尼和替莫唑胺：儿童肿瘤学组I期联合研究。
2. A phase 1b study of erlotinib in combination with gemcitabine and nab-paclitaxel in patients with previously untreated advanced pancreatic cancer: an Academic Oncology GI Cancer Consortium study [J] . Cohen Steven J., ONeil Bert H., Berlin Jordan, Cancer chemotherapy and pharmacology. . 2016,第4期

机译：厄洛替尼联合吉西他滨和纳布紫杉醇在先前未经治疗的晚期胰腺癌患者中的1b阶段研究：学术肿瘤胃肠道癌症联合研究
3. Safety, tolerability and pharmacokinetics of crizotinib in combination with cytotoxic chemotherapy for pediatric patients with refractory solid tumors or anaplastic large cell lymphoma (ALCL): a Children's Oncology Group phase 1 consortium study (ADVL1212) [J] . Greengard Emily, Mosse Yael P., Liu Xiaowei, Cancer chemotherapy and pharmacology. . 2020,第6期

机译：Crizotinib的安全性，耐受性和药代动力学与细胞毒性化疗组合难治性固体肿瘤或血栓性大细胞淋巴瘤（ALCL）：儿童肿瘤组阶段1财团研究（ADVL1212）
4. On the Use of Change in Tumor Size to Predict Survival in Clinical Oncology Studies:Toward a New Paradigm to Design and Evaluate Phase II Studies [C] . R Bruno, L Claret 21st international conference on screening for lung cancer . 2009

机译：在临床肿瘤学研究中利用肿瘤大小的变化预测存活率：建立设计和评估II期研究的新范例
5. A phase I study of vincristine, escalating doses of irinotecan, temozolomide and bevacizumab (VIT-B) in pediatric and adolescent patients with recurrent or refractory solid tumors of non-hematopoietic origin [D] . Venkatramani, Rajkumar. 2010

机译：长春新碱，伊非替康，替莫唑胺和贝伐单抗（VIT-B）逐步剂量在患有非造血源性复发或难治性实体瘤的儿童和青少年患者中的I期研究
6. Pediatric Phase I Trial and Pharmacokinetic Study of MLN8237 an Investigational Oral Selective Small-Molecule Inhibitor of Aurora Kinase A: A Childrens Oncology Group Phase I Consortium Study [O] . Yael P. Mossé, Emily Lipsitz, Elizabeth Fox, -1

机译：小儿I期临床试验和mLN8237极光激酶a的一个试验用口服选择性小分子抑制剂的药代动力学研究：儿童肿瘤学组I期研究联盟
7. Pediatric Phase I and Pharmacokinetic Study of Erlotinib Followed by the Combination of Erlotinib and Temozolomide: A Children's Oncology Group Phase I Consortium Study [O] . Jakacki, Regina I., Hamilton, Marta, Gilbertson, Richard J., 2008

机译：厄洛替尼的儿科I期和药代动力学研究，随后厄洛替尼与替莫唑胺合用：儿童肿瘤学组I期联合研究

Pediatric Phase I and Pharmacokinetic Study of Erlotinib Followed by the Combination of Erlotinib and Temozolomide: A Childrens Oncology Group Phase I Consortium Study

摘要

著录项

相似文献

相关主题

期刊订阅