Clinical Utility of Simultaneous Quantitation of 25-Hydroxyvitamin D and 2425-Dihydroxyvitamin D by LC-MS/MS Involving Derivatization With DMEQ-TAD

机译：LC-MS / MS涉及DMEQ-TAD衍生化的同时定量25-羟基维生素D和2425-二羟基维生素D的临床效用

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Context:The discovery of hypercalcemic diseases due to loss-of-function mutations in 25-hydroxyvitamin D-24-hydroxylase has placed a new demand for sensitive and precise assays for 24,25-dihydroxyvitamin D [24,25-(OH)2D].

机译：背景：由于25-羟基维生素D-24-羟化酶功能丧失突变引起的高钙血症疾病的发现，对24,25-二羟基维生素D [24,25-（OH）2D的灵敏且精确的测定提出了新的要求]。

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期刊名称 The Journal of Clinical Endocrinology and Metabolism
作者
Martin Kaufmann; J. Christopher Gallagher; Munro Peacock; Karl-Peter Schlingmann; Martin Konrad; Hector F. DeLuca; Rita Sigueiro; Borja Lopez; Antonio Mourino; Miguel Maestro; René St-Arnaud; Joel S. Finkelstein; Donald P. Cooper; Glenville Jones;
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年(卷),期 -1(99),7
年度 -1
页码 2567–2574
总页数 8
原文格式 PDF
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中图分类基础医学;
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1. Clinical Utility of Simultaneous Quantitation of 25-Hydroxyvitamin D and 24,25-Dihydroxyvitamin D by LC-MS/MS Involving Derivatization With DMEQ-TAD [J] . Martin Kaufmann, J. Christopher Gallagher, Munro Peacock, The journal of clinical endocrinology and metabolism . 2014,第7期

机译：LC-MS / MS涉及DMEQ-TAD衍生化的同时定量25-羟基维生素D和24,25-二羟基维生素D的临床效用
2. Clinical Utility of Simultaneous Quantitation of 25-Hydroxyvitamin D and 24,25-Dihydroxyvitamin D by LC-MS/MS Involving Derivatization With DMEQ-TAD [J] . Martin Kaufmann, J. Christopher Gallagher, Munro Peacock, The journal of clinical endocrinology and metabolism . 2014,第7期

机译：LC-MS / MS涉及DMEQ-TAD衍生化的同时定量25-羟基维生素D和24,25-二羟基维生素D的临床效用
3. Quantitation of 25-hydroxyvitamin D in dried blood spots by 2D LC-MS/MS without derivatization and correlation with serum in adult and pediatric studies [J] . Jensen Bent P., Saraf Rajneeta, Ma Jing, Clinica chimica acta: International journal of clinical chemistry and applied molecular biology . 2018,第期

机译：2D LC-MS / MS在干燥血液中定量25-羟基羟胞蛋白D，而不会衍生化和与成人和儿科研究中的血清相关性
4. A New LC-MS Approach for Generic Screening and Quantitation of Potential Genotoxic Alkylation Compounds without Derivatization. [C] . Pierangela Palma, Giorgio Famiglini, Veronica Termopoli, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2011

机译：一种新的LC-MS方法，用于通用筛选和定量潜在的遗传毒性烷基化化合物，无衍生化。
5. Derivatization Methods for Improved Metabolome Analysis by LC-MS/MS [D] . Malec, Paige A. 2018

机译：通过LC-MS / MS改进代谢组学分析的衍生化方法
6. Sensitive Simultaneous Quantitation of Testosterone and Estradiol in Serum by LC-MS/MS without Derivatization and Comparison with the CDC HoSt Program [O] . Ryan C. Schofield, Damodara R. Mendu, Lakshmi V. Ramanathan, -1

机译：无需衍生化的LC-MS / MS灵敏同时定量血清中的睾丸激素和雌二醇并与CDC HoSt程序进行比较
7. Clinical utility of simultaneous quantitation of 25-hydroxyvitamin D and 24,25-dihydroxyvitamin D by LC-MS/MS involving derivatization with DMEQ-TAD [O] . Kaufmann, Martin, Gallagher, J. Christopher, Peacock, Munro, 2014

机译：LC-MS / MS同时定量25-羟基维生素D和24,25-二羟基维生素D的临床应用，涉及DMEQ-TAD衍生化

Clinical Utility of Simultaneous Quantitation of 25-Hydroxyvitamin D and 2425-Dihydroxyvitamin D by LC-MS/MS Involving Derivatization With DMEQ-TAD

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