Cystatin C– and Creatinine-Based Estimated Glomerular Filtration Rate Vascular Disease and Mortality in Persons With Diabetes in the U.S.

摘要

OBJECTIVESerum cystatin C is an alternative to serum creatinine for estimating glomerular filtration rate (GFR), since cystatin C is less influenced by age and muscle mass. Among persons with diabetes, we compared the performance of GFR estimated using cystatin C (eGFRcys) with that using creatinine (eGFRcr) for the identification of reduced kidney function and its association with diabetes complications.