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Advances in molecular imaging of atherosclerosis and myocardial infarction: shedding new light on in vivo cardiovascular biology

机译:动脉粥样硬化和心肌梗死的分子成像研究进展:为体内心血管生物学开辟了新天地

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摘要

Molecular imaging of the cardiovascular system heavily relies on the development of new imaging probes and technologies to facilitate visualization of biological processes underlying or preceding disease. Molecular imaging is a highly active research discipline that has seen tremendous growth over the past decade. It has broadened our understanding of oncologic, neurologic, and cardiovascular diseases by providing new insights into the in vivo biology of disease progression and therapeutic interventions. As it allows for the longitudinal evaluation of biological processes, it is ideally suited for monitoring treatment response. In this review, we will concentrate on the major accomplishments and advances in the field of molecular imaging of atherosclerosis and myocardial infarction with a special focus on magnetic resonance imaging.
机译:心血管系统的分子成像在很大程度上依赖于新的成像探针和技术的开发,以促进可视化潜在或先前疾病的生物过程。分子成像是一门活跃的研究学科,在过去的十年中取得了巨大的发展。通过提供对疾病进展和治疗干预的体内生物学的新见解,它拓宽了我们对肿瘤,神经和心血管疾病的理解。由于它允许对生物过程进行纵向评估,因此非常适合监视治疗反应。在这篇综述中,我们将集中在动脉粥样硬化和心肌梗死的分子成像领域的主要成就和进展,特别是磁共振成像。

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