Stem Cell Conditioned Culture Media Attenuated Albumin-Induced Epithelial– Mesenchymal Transition in Renal Tubular Cells

机译：干细胞条件培养基减弱了肾小管细胞中白蛋白诱导的上皮-间质转化

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BackgroundProteinuria-induced epithelial-mesenchymal transition (EMT) plays an important role in progressive renal tubulointerstitial fibrosis in chronic renal disease. Stem cell therapy has been used for different diseases. Stem cell conditioned culture media (SCM) exhibits similar beneficial effects as stem cell therapy. The present study tested the hypothesis that SCM inhibits albumin-induced EMT in cultured renal tubular cells.

机译：背景蛋白尿引起的上皮-间质转化（EMT）在慢性肾脏疾病的进行性肾小管间质纤维化中起重要作用。干细胞疗法已用于不同的疾病。干细胞条件培养基（SCM）表现出与干细胞疗法相似的有益效果。本研究检验了SCM抑制培养的肾小管细胞中白蛋白诱导的EMT的假设。

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期刊名称 Cellular Physiology and Biochemistry
作者
Junping Hu; Qing Zhu; Pin-Lan Li; Weili Wang; Fan Yi; Ningjun Li;
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作者单位

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年(卷),期 -1(35),5
年度 -1
页码 1719–1728
总页数 18
原文格式 PDF
正文语种
中图分类细胞生物学;人体生理学;
关键词
E-cadherin Fibroblast-specific protein 1 α-smooth muscle actin NF-κB;

机译：E-钙黏着蛋白;成纤维细胞特异性蛋白1;α-平滑肌肌动蛋白;NF-κB;
入库时间 2022-08-21 10:50:59

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专利

1. Stem Cell Conditioned Culture Media Attenuated Albumin-Induced Epithelial-Mesenchymal Transition in Renal Tubular Cells [J] . Hu J., Li N., Li P.-L., Cellular Physiology and Biochemistry . 2015,第5期

机译：干细胞条件培养基减弱肾小管细胞中白蛋白诱导的上皮-间充质转化。
2. Astragaloside IV attenuates glycated albumin-induced epithelial-to-mesenchymal transition by inhibiting oxidative stress in renal proximal tubular cells [J] . Weiwei Qi, Jianying Niu, Qiaojing Qin, Cell stress & chaperones . 2014,第1期

机译：黄芪甲苷IV通过抑制肾近端肾小管细胞的氧化应激而减弱糖化白蛋白诱导的上皮-间充质转化
3. HOXA13 exerts a beneficial effect in albumin-induced epithelial-mesenchymal transition via the glucocorticoid receptor signaling pathway in human renal tubular epithelial cells [J] . Peng Li, He Qingnan, Li Xiaoyan, Molecular medicine reports . 2016,第1aPta1期

机译：HOXA13通过糖皮质激素受体信号通路在人肾小管上皮细胞中对白蛋白诱导的上皮-间质转化发挥有益作用
4. Co-culture of Mesenchymal Stem Cells and Respiratory Epithelial Cells to Engineer a Human Tracheal Mucosa [C] . Catherine Le Visage, Brian Dunham, Paul Flint, Annual meeting of the Society For Biomaterials . 2003

机译：间充质干细胞和呼吸道上皮细胞的共培养，以工程化人气管粘膜
5. The JAK2/Y343/STAT 5 signaling axis is required for erythropoietin-mediated protection against ischemic injury in renal tubular epithelial cells. [D] . Breggia, Anne C. 2008

机译：JAK2 / Y343 / STAT 5信号轴是促红细胞生成素介导的抗肾小管上皮细胞缺血性损伤的保护所必需的。
6. Astragaloside IV attenuates glycated albumin-induced epithelial-to-mesenchymal transition by inhibiting oxidative stress in renal proximal tubular cells [O] . Weiwei Qi, Jianying Niu, Qiaojing Qin, 2014

机译：黄芪甲苷IV通过抑制肾脏近端肾小管细胞的氧化应激而减弱糖化白蛋白诱导的上皮-间充质转化
7. Stem Cell Conditioned Culture Media Attenuated Albumin-Induced Epithelial-Mesenchymal Transition in Renal Tubular Cells [O] . Junping Hu, Qing Zhu, Pin-Lan Li, 2015

机译：干细胞条件培养基减轻白蛋白诱导的肾小管细胞上皮 - 间质转化
8. Origin of Prostate Cancer Stem Cells through Transmissible ER Stress-Mediated Epithelial to Mesenchymal Transition. [R] . J. Rodvold K. Chiu M. Zanetti 2013

机译：前列腺癌干细胞通过可传递的ER应激介导的上皮细胞向间充质细胞转化的起源。

Stem Cell Conditioned Culture Media Attenuated Albumin-Induced Epithelial– Mesenchymal Transition in Renal Tubular Cells

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