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Determination of artemether and dihydroartemisinin in human plasma with a new hydrogen peroxide stabilization method

机译：一种新的过氧化氢稳定化方法测定人血浆中的蒿甲醚和双氢青蒿素

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摘要

BackgroundNumerous methods have been reported for the determination of artemether (ARM) and its metabolite dihydroartemisinin (DHA) in plasma. However, stability issues in patient plasma have not received enough attention.

机译：背景技术已经报道了许多测定血浆中蒿甲醚（ARM）及其代谢物双氢青蒿素（DHA）的方法。但是，患者血浆中的稳定性问题尚未引起足够的重视。

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期刊名称 Bioanalysis
作者
Liusheng Huang; Alexander Olson; David Gingrich; Francesca T Aweeka;
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作者单位

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年(卷),期 -1(5),12
年度 -1
页码 91
总页数 13
原文格式 PDF
正文语种
中图分类生化遗传学;生化药理学;药物化学;
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专利

1. Determination of artemether and dihydroartemisinin in human plasma with a new hydrogen peroxide stabilization method [J] . HuangL., OlsonA., GingrichD., Bioanalysis . 2013,第12期

机译：一种新的过氧化氢稳定化方法测定人血浆中的蒿甲醚和双氢青蒿素
2. A High-Resolution LC-MS/MS Method for the Quantitative Determination of Artemether and Its Metabolite Dihydroartemisinin in Human Plasma and Its Application to Pharmacokinetic Studies (vol 79, pg 609, 2016) [J] . Khuda Fazli, Iqbal Zafar, Shah Yasar, Chromatographia . 2016,第9a10期

机译：高分辨率LC-MS / MS方法定量测定人血浆中的蒿甲醚及其代谢产物双氢青蒿素及其在药代动力学研究中的应用（第79卷，第609页，2016年）
3. A High-Resolution LC-MS/MS Method for the Quantitative Determination of Artemether and Its Metabolite Dihydroartemisinin in Human Plasma and Its Application to Pharmacokinetic Studies (vol 79, pg 609, 2016) [J] . Khuda Fazli, Iqbal Zafar, Shah Yasar, Chromatographia . 2016,第9a10期

机译：高分辨率LC-MS / MS方法定量测定人血浆中的蒿甲醚及其代谢产物双氢青蒿素及其在药代动力学研究中的应用（第79卷，第609页，2016年）
4. A Selective and Sensitive Liquid Chromatography - Tandem Mass Spectrometry Method for the Determination of Artemether and DHA in Human Plasma [C] . Gary Gabriels, Katya Govender, Karen Barnes, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2010

机译：一种选择性和敏感的液相色谱 - 串联质谱法测定人血浆中的蒿纤维和DHA
5. Methods for Plasma Stabilization and Control to Improve Antihydrogen Production [D] . Carruth, Celeste. 2018

机译：等离子体稳定性和对抗改善抗氢化产量的方法
6. Development and validation of a high-performance liquid chromatography/tandem mass spectrometry method for the determination of artemether and its active metabolite dihydroartemisinin in human plasma [O] . Liusheng Huang, Anura L. Jayewardene, Xiaohua Li, -1

机译：高效液相色谱/串联质谱法测定人血浆中蒿及其活性代谢二氢肝炎素的高效液相色谱/串联质谱法的发展及验证
7. Erratum to: A High-Resolution LC–MS/MS Method for the Quantitative Determination of Artemether and Its Metabolite Dihydroartemisinin in Human Plasma and Its Application to Pharmacokinetic Studies [O] . Fazli Khuda, Zafar Iqbal, Yasar Shah, 2016

机译：错误：一种高分辨率LC-MS / MS / MS方法，用于定量测定人血浆中的蒿纤维醚及其代谢物二氢氨基苷及其对药代动力学研究的应用

Determination of artemether and dihydroartemisinin in human plasma with a new hydrogen peroxide stabilization method

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