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Adjuvant bevacizumab for melanoma patients at high risk of recurrence: survival analysis of the AVAST-M trial

机译：贝伐单抗辅助治疗高复发风险的黑色素瘤患者：AVAST-M试验的生存分析

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摘要

BackgroundBevacizumab is a recombinant humanised monoclonal antibody to vascular endothelial growth factor shown to improve survival in advanced solid cancers. We evaluated the role of adjuvant bevacizumab in melanoma patients at high risk of recurrence.

机译：背景贝伐单抗是针对血管内皮生长因子的重组人源化单克隆抗体，显示可改善晚期实体癌的生存率。我们评估了贝伐单抗辅助剂在高复发风险的黑色素瘤患者中的作用。

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期刊名称 Annals of Oncology
作者
P G Corrie; A Marshall; P D Nathan; P Lorigan; M Gore; S Tahir; G Faust; C G Kelly; M Marples; S J Danson; E Marshall; S J Houston; R E Board; A M Waterston; J P Nobes; M Harries; S Kumar; A Goodman; A Dalgleish; A Martin-Clavijo; S Westwell; R Casasola; D Chao; A Maraveyas; P M Patel; C H Ottensmeier; D Farrugia; A Humphreys; B Eccles; G Young; E O Barker; C Harman; M Weiss; K A Myers; A Chhabra; S H Rodwell; J A Dunn; M R Middleton; Paul Nathan; Paul Lorigan; Peter Dziewulski; Sonja Holikova; Udaiveer Panwar; Saad Tahir; Guy Faust; Anne Thomas; Pippa Corrie; Bhawna Sirohi; Charles Kelly; Mark Middleton; Maria Marples; Sarah Danson; James Lester; Ernest Marshall; Mazhar Ajaz; Stephen Houston; Ruth Board; David Eaton; Ashita Waterston; Jenny Nobes; Suat Loo; Gill Gray; Helen Stubbings; Martin Gore; Mark Harries; Satish Kumar; Andrew Goodman; Angus Dalgleish; Agustin Martin-Clavijo; Jerry Marsden; Sarah Westwell; Richard Casasola; David Chao; Anthony Maraveyas; Ernest Marshall; Poulam Patel; Christian Ottensmeier; David Farrugia; Alison Humphreys; Bryony Eccles; Renata Dega; Chris Herbert; Christopher Price; Murray Brunt; Martin Scott-Brown; Joanna Hamilton; Richard Larry Hayward; John Smyth; Pamela Woodings; Neena Nayak; Lorna Burrows; Virginia Wolstenholme; John Wagstaff; Marianne Nicolson; Andrew Wilson; Clare Barlow; Christopher Scrase; Timothy Podd; Michael Gonzalez; John Stewart; Martin Highley; Virginia Wolstenholme; Simon Grumett; Andrew Goodman; Toby Talbot; Kannon Nathan; Robert Coltart; Bruce Gee; Martin Gore; David Farrugia; Agustin Martin-Clavijo; Jerry Marsden; Christopher Price; David Farrugia; Kannon Nathan; Robert Coltart; Kannon Nathan; Robert Coltart;
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年(卷),期 -1(29),8
年度 -1
页码 1843–1852
总页数 10
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
melanoma bevacizumab adjuvant therapy;

机译：黑色素瘤;贝伐单抗;辅助治疗;

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专利

1. Adjuvant bevacizumab for melanoma patients at high risk of recurrence: survival analysis of the AVAST-M trial [J] . Corrie P. G., Marshall A., Nathan P. D., Annals of oncology: official journal of the European Society for Medical Oncology . 2018,第8期

机译：黑色素瘤患者的佐剂贝伐单抗高患者的复发风险：AVAST-M试验的存活分析
2. Adjuvant bevacizumab in patients with melanoma at high risk of recurrence (AVAST-M): Preplanned interim results from a multicentre, open-label, randomised controlled phase 3 study [J] . CorrieP.G., MarshallA., DunnJ.A., The lancet oncology . 2014,第6期

机译：高复发风险黑色素瘤患者的佐剂贝伐单抗（AVAST-M）：一项来自多中心，开放标签，随机对照3期研究的计划中期结果
3. 6010 A three-arm phase III randomized trial of FOLFOX-4 vs. FOLFOX-4 plus bevacizumab vs. XELOX plus bevacizumab in the adjuvant treatment of patients with stage III or high-risk stage II colon cancer: results of the interim safety analysis of the AVANT trial [J] . P.Hoff, S.Clarke, D.Cunningham, European Journal of Cancer Supplements . 2009,第2期

机译：6010 FOLFOX-4与FOLFOX-4联合贝伐单抗与XELOX联合贝伐单抗进行的三臂III期随机试验在III期或高危II期结肠癌患者的辅助治疗中的应用： AVANT试用
4. RISK-ADAPTED INTRAVENOUS MELPHALAN WITH ADJUVANT THALIDOMIDE AND DEXAMETHASONE FOR NEWLY DIAGNOSED UNTREATED PATIENTS WITH SYSTEMIC AL AMYLOIDOSIS: INTERIM REPORT OF A PHASE II TRIAL [C] . RL Comenzo, P Zhou, L Reich, International Symposium on Amyloidosis . 2005

机译：风险适应的静脉内莫尔甘蔗用佐剂沙利度胺和地塞米松，用于新诊断的未经治疗的全身淀粉样蛋白症患者：II期试验的中期报告
5. Associating Computed Tomography (CT) Imaging Response Criteria and Texture Analysis Measurements with Survival in Patients with Metastatic Melanoma Treated with Anti-angiogenic Therapy. [D] . Gray, Mark Russell. 2014

机译：将计算机断层扫描（CT）成像反应标准和纹理分析测量值与接受抗血管生成治疗的转移性黑色素瘤患者的生存率相关联。
6. Adjuvant bevacizumab for melanoma patients at high risk of recurrence: survival analysis of the AVAST-M trial [O] . P G Corrie, A Marshall, P D Nathan, -1

机译：贝伐单抗辅助治疗高复发风险的黑色素瘤患者：AVAST-M试验的生存分析
7. Adjuvant bevacizumab in patients with melanoma at high risk of recurrence (AVAST-M) : preplanned interim results from a multicentre, open-label, randomised controlled phase 3 study [O] . Corrie, Pippa G., Marshall, A. (Andrea)‏, Dunn, Janet A., 2014

机译：高复发风险黑色素瘤患者的佐剂贝伐单抗（AVAST-M）：一项多中心，开放标签，随机对照3期研究的预先计划的中期结果

Adjuvant bevacizumab for melanoma patients at high risk of recurrence: survival analysis of the AVAST-M trial

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