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Alcohol Consumption in Young Adults and Incident Hypertension: 20-Year Follow-up From the Coronary Artery Risk Development in Young Adults Study

机译:青年成年人的饮酒量和突发性高血压:青年成年人冠状动脉风险发展研究的20年随访

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摘要

The relation between alcohol consumption and incident hypertension is unclear, and most observational studies have not accounted for socioeconomic factors. This study examined the association between alcohol consumption in a diverse group of young adults and incident hypertension over 20 years. Participants (n = 4,711) were from the Coronary Artery Risk Development in Young Adults Study cohort, recruited in 1985 (aged 18–30 years) from Birmingham, Alabama; Chicago, Illinois; Minneapolis, Minnesota; and Oakland, California. The 20-year incidence of hypertension for never, former, light, moderate, and at-risk drinkers was 25.1%, 31.8%, 20.9%, 22.2%, and 18.8%, respectively (P < 0.001). Race, gender, age, family history of hypertension, body mass index, income, education, and difficulty paying for basics and medical care were associated with hypertension. Adjustment using Cox proportional hazard models revealed no association between baseline alcohol consumption and incident hypertension, except among European-American women in whom any current alcohol consumption was associated with lower risk of incident hypertension. The lack of association between alcohol and hypertension in the majority of this socioeconomically diverse cohort is not definitive. Future studies should include social factors, such as income and education, and consider additional characteristics that may modify or confound associations between alcohol and blood pressure.
机译:饮酒与突发性高血压之间的关系尚不清楚,并且大多数观察性研究并未考虑社会经济因素。这项研究调查了20年来不同年龄段的年轻人的饮酒与突发性高血压之间的关系。参与者(n = 4,711)来自于1985年从阿拉巴马州伯明翰市(年龄为18至30岁)招募的年轻成年人冠状动脉风险发展研究队列。伊利诺伊州芝加哥;明尼苏达州明尼阿波利斯;和加利福尼亚奥克兰。从不饮酒,前饮酒,轻度饮酒,中度饮酒和高危饮酒者的20年高血压发生率分别为25.1%,31.8%,20.9%,22.2%和18.8%(P <0.001)。种族,性别,年龄,高血压家族史,体重指数,收入,教育程度,基本医疗费用和支付困难与高血压有关。使用Cox比例风险模型进行的调整显示,基线饮酒量与突发性高血压之间没有关联,除了在欧美女性中,当前任何饮酒与发生高血压的风险较低相关。在这个社会经济差异很大的人群中,酒精和高血压之间缺乏关联并不是确定的。未来的研究应包括诸如收入和教育等社会因素,并考虑可能会改变或混淆酒精与血压关联的其他特征。

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