首页> 美国卫生研究院文献>Annals of the American Thoracic Society >Home-based Physical Activity Coaching Physical Activity and Health Care Utilization in Chronic Obstructive Pulmonary Disease. Chronic Obstructive Pulmonary Disease Self-Management Activation Research Trial Secondary Outcomes
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Home-based Physical Activity Coaching Physical Activity and Health Care Utilization in Chronic Obstructive Pulmonary Disease. Chronic Obstructive Pulmonary Disease Self-Management Activation Research Trial Secondary Outcomes

机译:慢性阻塞性肺疾病的家庭体育锻炼体育锻炼和卫生保健利用。慢性阻塞性肺疾病自我管理激活研究试验继发结果

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摘要

>Rationale: Physical inactivity among patients with chronic obstructive pulmonary disease is associated with exacerbations requiring high-cost health care utilization including urgent, emergent, and hospital care.>Objectives: To examine the effectiveness of a behavioral lifestyle physical activity intervention combined with chronic obstructive pulmonary disease self-management education to prevent high-cost health care utilization.>Methods: This was an analysis of secondary outcomes of the Chronic Obstructive Pulmonary Disease Self-Management Activation Research Trial, a two-arm randomized trial of stable adult outpatients with chronic obstructive pulmonary disease recruited from primary care and pulmonary clinics. Following a 6-week self-management education run-in period, participants were randomized to usual care or to a telephone-delivered home-based health coaching intervention over 20 weeks. Secondary outcomes of physical activity and health care utilization were determined by self-report 6, 12, and 18 months after randomization. Associations between treatment allocation arm and these secondary outcomes were examined using log-binomial and Poisson regression models.>Results: A total of 325 outpatients with stable chronic obstructive pulmonary disease were enrolled in the trial. Their average age was 70.3 years (standard deviation, 9.5), and 50.5% were female; 156 were randomized to usual care and 149 to the intervention. A greater proportion of participants reported being persistently active over the 18-month follow-up period in the intervention group (73.6%) compared with the usual care group (57.8%) (mean difference, 15.8%; 95% confidence interval, 4.0–27.7%). This association varied by severity of forced expiratory volume in 1 second impairment (P for interaction = 0.09). Those in the intervention group with moderate impairment (forced expiratory volume in 1 second, 50–70% predicted), more frequently reported being persistently active compared with the usual care (86.0 vs. 65.1%; mean difference, 20.9%; 95% confidence interval, 5.7–36.1%). Patients with severe and very severe forced expiratory volume in 1 second impairment (forced expiratory volume in 1 second < 50% predicted) in the intervention group also reported being persistently active more frequently compared with usual care (63.3 vs. 50.8%; mean difference, 12.6%; 95% confidence interval, –4.7 to 29.8). The intervention was associated with a lower rate of lung-related utilization (adjusted rate ratio, 0.38; 95% confidence interval, 0.23–0.63) only among participants with severe spirometric impairment.>Conclusions: Our results demonstrate that a feasible and generalizable home-based coaching intervention may decrease sedentary behavior and increase physical activity levels. In those with severe chronic obstructive pulmonary disease, this intervention may reduce lung disease–related health care utilization.Clinical trial registered with ().
机译:>理由:慢性阻塞性肺疾病患者的身体不活动与需要加重医疗费用(包括紧急,急诊和医院护理)的病情加重有关。>目的:行为生活方式体育锻炼干预与慢性阻塞性肺疾病自我管理教育相结合对预防高成本卫生保健利用的有效性。>方法:这是对慢性阻塞性肺疾病自我的次要结果的分析-Management Activation Research Trial,一项从初级保健和肺部诊所招募的稳定的患有慢性阻塞性肺疾病的成人门诊病人的两臂随机试验。在进行为期6周的自我管理教育磨合期后,参与者在20周内被随机分配到常规护理或通过电话进行的基于家庭的健康指导干预。身体活动和医疗保健利用的次要结果由随机分组后6、12和18个月的自我报告确定。使用对数二项式和Poisson回归模型检查了治疗分配组与这些次要结局之间的关联。>结果:该研究共纳入325名稳定的慢性阻塞性肺疾病门诊患者。他们的平均年龄为70.3岁(标准差为9.5),女性为50.5%; 156例被随机分配到常规护理,149例被随机分配到干预措施。与常规护理组(57.8%)相比,干预组在18个月随访期间持续活动的参与者比例(73.6%)更大(平均差异15.8%; 95%置信区间4.0– 27.7%)。这种关联因1秒障碍中的呼气量的严重程度而异(相互作用的P = 0.09)。干预组中的中度损伤患者(强迫呼气量在1秒内,预计为50-70%),与常规护理相比,更经常报告为持续活动(86.0 vs. 65.1%;平均差异,20.9%; 95%置信度区间5.7–36.1%)。干预组在1秒内有严重和非常严重的强制呼气量(预计在1秒内强制呼气量 50%)的患者也报告说,与常规护理相比,其持续活动的频率更高(63.3 vs. 50.8%;平均差异, 12.6%; 95%置信区间,-4.7至29.8)。仅在严重肺功能受损的参与者中,该干预措施与较低的肺相关利用率相关(调整率比率为0.38; 95%置信区间为0.23-0.63)。>结论:可行且可推广的家庭式教练干预措施可能会减少久坐的行为并增加身体活动水平。在患有严重慢性阻塞性肺疾病的患者中,这种干预措施可能会减少与肺疾病相关的医疗保健利用率。临床试验已向()注册。

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