Targeting sphingosine kinase 2 (SphK2) by ABC294640 inhibits colorectal cancer cell growth in vitro and in vivo

机译：ABC294640靶向鞘氨醇激酶2（SphK2）在体外和体内抑制结肠直肠癌细胞的生长

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BackgroundColorectal cancer (CRC) is a major health problem in China and around the world. It is one of the leading causes of cancer-related deaths. Research groups are thus searching for novel and more efficient anti-CRC agents.

机译：背景大肠癌（CRC）是中国乃至全球的主要健康问题。它是癌症相关死亡的主要原因之一。因此，研究小组正在寻找新颖且更有效的抗CRC药物。

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期刊名称 Journal of Experimental Clinical Cancer Research : CR
作者
Cai Xun; Min-Bin Chen; Li Qi; Zhang Tie-Ning; Xue Peng; Li Ning; Chen Zhi-Xiao; Wang Li-Wei;
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作者单位

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年(卷),期 2015(34),1
年度 2015
页码 94
总页数 9
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
Colorectal cancer Sphingosine kinase ABC294640 Ceramide and signaling;

机译：大肠癌;鞘氨醇激酶;ABC294640;神经酰胺和信号传导;

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专利

1. Targeting sphingosine kinase 2 (SphK2) by ABC294640 inhibits colorectal cancer cell growth in vitro and in vivo [J] . Cai Xun, Min-Bin Chen, Li Qi, Journal of experimental & clinical cancer research : . 2015,第1期

机译：通过ABC294640靶向鞘氨醇激酶2（SphK2）在体外和体内抑制结肠直肠癌细胞的生长
2. The Sphingosine Kinase 2 Inhibitor ABC294640 Reduces the Growth of Prostate Cancer Cells and Results in Accumulation of Dihydroceramides In Vitro and In Vivo [J] . Venant Heather, Rahmaniyan Mehrdad, Jones E. Ellen, Molecular cancer therapeutics . 2015,第12期

机译：鞘氨醇激酶2抑制剂ABC294640减少前列腺癌细胞的生长并导致体内和体外积累二氢神经酰胺
3. The sphingosine kinase 2 inhibitor ABC294640 displays anti‐non‐small cell lung cancer activities in vitro in vitro and in vivo in vivo [J] . Dai Lu, Smith Charles D., Foroozesh Maryam, International Journal of Cancer =: Journal International du Cancer . 2018,第10期

机译：鞘氨醇激酶2抑制剂ABC294640在体外和体内体内显示抗非小细胞肺癌活动
4. Small Molecule ONC201/TIC10 Targets Chemotherapy-Resistant Colorectal Cancer Stem Cells In Vitro and In Vivo [C] . Varun Vijay Prabhu, Joshua E. Allen, David T. Dicker, Molecular Medicine TRI-CON. . 2014

机译：小分子ONC201 / TIC10在体外和体内靶向化疗抗性结肠直肠癌干细胞
5. A Src-Abl kinase inhibitor, SKI-606, blocks breast cancer invasion, growth and metastasis in vitro and in vivo [D] . Jallal, Houda 2008

机译：SRC-ABL激酶抑制剂，SKI-606，体外和体内阻断乳腺癌侵袭，生长和转移
6. The sphingosine kinase 2 inhibitor ABC294640 reduces the growth of prostate cancer cells and results in accumulation of dihydroceramides in vitro and in vivo [O] . Heather Venant, Mehrdad Rahmaniyan, E. Ellen Jones, -1

机译：鞘氨醇激酶2抑制剂ABC294640减少前列腺癌细胞的生长并导致体内外二氢神经酰胺的积累
7. Targeting sphingosine kinase 2 (SphK2) by ABC294640 inhibits colorectal cancer cell growth in vitro and in vivo [O] . Cai Xun, Min-Bin Chen, Li Qi, 2015

机译：通过ABC294640靶向鞘氨醇激酶2（SphK2）在体外和体内抑制结肠直肠癌细胞的生长

Targeting sphingosine kinase 2 (SphK2) by ABC294640 inhibits colorectal cancer cell growth in vitro and in vivo

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