EGFR-specific T cell frequencies correlate with EGFR expression in head and neck squamous cell carcinoma

机译：EGFR特异的T细胞频率与头颈部鳞状细胞癌中EGFR表达相关

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BackgroundIn head and neck squamous cell carcinoma (HNSCC), expression levels of the epidermal growth factor receptor (EGFR) correlate with poor prognosis and decreased survival rates. As the mechanisms responsible for cellular immune response to EGFR in vivo remain unclear, the frequency and function of EGFR-specific cytotoxic T cells (CTL) was determined in HNSCC patients.

机译：背景技术在头颈部鳞状细胞癌（HNSCC）中，表皮生长因子受体（EGFR）的表达水平与预后不良和生存率降低相关。由于尚不清楚负责体内对EGFR细胞免疫应答的机制，因此确定了HNSCC患者中EGFR特异性细胞毒性T细胞（CTL）的频率和功能。

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期刊名称 Journal of Translational Medicine
作者
Patrick J Schuler; Petra Boeckers; Rainer Engers; Edwin Boelke; Murat Bas; Jens Greve; Claudia A Dumitru; Goetz F Lehnerdt; Robert L Ferris; Pedro A Andrade Filho; Sven Brandau; Stephan Lang; Theresa L Whiteside; Thomas K Hoffmann;
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作者单位

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年(卷),期 2011(9),-1
年度 2011
页码 168
总页数 8
原文格式 PDF
正文语种
中图分类医学史;
关键词
EGFR head and neck carcinoma tetramer EGFR-specific T cells;

机译：EGFR;头颈癌;四聚体;EGFR特异性T细胞;
入库时间 2022-08-21 10:49:55

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专利

1. EGFR-specific T cell frequencies correlate with EGFR expression in head and neck squamous cell carcinoma [J] . Patrick J Schuler, Petra Boeckers, Rainer Engers, Journal of Translational Medicine . 2011,第1期

机译：EGFR特异的T细胞频率与头颈部鳞状细胞癌中EGFR表达相关
2. Role of polymorphic Fc gamma receptor IIIa and EGFR expression level in cetuximab mediated, NK cell dependent in vitro cytotoxicity of head and neck squamous cell carcinoma cells [J] . López-AlbaiteroA., LeeS.C., MorganS., Cancer immunology, immunotherapy : . 2009,第11期

机译：多态性Fcγ受体IIIa和EGFR表达水平在西妥昔单抗介导的NK细胞依赖的头颈部鳞状细胞癌细胞体外细胞毒性中的作用
3. Role of polymorphic Fc gamma receptor IIIa and EGFR expression level in cetuximab mediated, NK cell dependent in vitro cytotoxicity of head and neck squamous cell carcinoma cells [J] . Andrés López-Albaitero, Steve C. Lee, Sarah Morgan, Cancer Immunology, Immunotherapy . 2009,第11期

机译：多态性Fcγ受体IIIa和EGFR表达水平在西妥昔单抗介导的NK细胞依赖的头颈部鳞状细胞癌细胞体外细胞毒性中的作用
4. A Bayesian Network Model of Head and Neck Squamous Cell Carcinoma Incorporating Gene Expression Profiles [C] . Shuyang Wu, Anthony Law, Mark E. Whipple MEDINFO . 2017

机译：兼容基因表达谱的头颈鳞状细胞癌的贝叶斯网络模型
5. Epidermal growth factor receptor (EGFR) gene expression and its related biomarkers in head and neck squamous cell carcinoma (HNSCC) [D] . Hauser, Belinda R. 2008

机译：表皮生长因子受体（EGFR）基因表达及其相关的生物标志物在头颈部鳞状细胞癌（HNSCC）中
6. Role of polymorphic Fc gamma receptor IIIa and EGFR expression level in cetuximab mediated NK cell dependent in vitro cytotoxicity of head and neck squamous cell carcinoma cells [O] . Andrés López-Albaitero, Steve C. Lee, Sarah Morgan, -1

机译：多晶型Fcγ受体IIIa和EGFR表达水平在西妥昔单抗介导的中的作用NK细胞依赖于头部和颈部鳞状细胞癌细胞的体外细胞毒性
7. EGFR-specific T cell frequencies correlate with EGFR expression in head and neck squamous cell carcinoma [O] . Ferris Robert L, Lehnerdt Goetz F, Dumitru Claudia A, 2011

机译：EGFR特异的T细胞频率与头颈部鳞状细胞癌中EGFR表达相关

EGFR-specific T cell frequencies correlate with EGFR expression in head and neck squamous cell carcinoma

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